A
Anna Lisa Giuliani
Researcher at University of Ferrara
Publications - 54
Citations - 2473
Anna Lisa Giuliani is an academic researcher from University of Ferrara. The author has contributed to research in topics: Receptor & Inflammation. The author has an hindex of 18, co-authored 45 publications receiving 1775 citations.
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Journal ArticleDOI
The P2X7 Receptor in Infection and Inflammation
TL;DR: The central role played by the P2X7 receptor in promoting inflammation and driving innate and adaptive immunity is discussed, with an in‐depth knowledge of its structure and of the associated signal transduction mechanisms needed for an effective therapeutic development.
Journal ArticleDOI
Expression of P2X7 Receptor Increases In Vivo Tumor Growth
Elena Adinolfi,Lizzia Raffaghello,Anna Lisa Giuliani,Luigi Cavazzini,Marina Capece,Paola Chiozzi,Giovanna Bianchi,Guido Kroemer,Vito Pistoia,Francesco Di Virgilio +9 more
TL;DR: It is found that P2X7 exhibits significant growth-promoting effects in vivo, and immunohistochemistry revealed strong P2x7 positivity in several human cancers.
Journal ArticleDOI
The P2X7 receptor: A main player in inflammation.
Elena Adinolfi,Anna Lisa Giuliani,Elena De Marchi,Anna Pegoraro,Elisa Orioli,Francesco Di Virgilio +5 more
TL;DR: The numerous intracellular pathways related to inflammation and activated by the P2X7R are described, including the NLRP3 inflammasome, NF‐kB, NFAT, GSK3&bgr; and VEGF, and the involvement of P2x7R in chronic diseases is discussed.
Journal ArticleDOI
Extracellular nucleotides and nucleosides as signalling molecules.
TL;DR: These processes confer a remarkable level of selectivity and plasticity to purinergic signalling that makes this network one of the most relevant extracellular messenger systems in higher organisms.
Journal ArticleDOI
P2 receptors and extracellular ATP: a novel homeostatic pathway in inflammation.
TL;DR: The purinergic signalling system is bound to yield novel therapeutic opportunities for the treatment of inflammatory diseases because it is comprised of extracellular ATP, P2 receptors and ecto-enzyme cascades.