L
Luigi Cavazzini
Researcher at University of Ferrara
Publications - 38
Citations - 3179
Luigi Cavazzini is an academic researcher from University of Ferrara. The author has contributed to research in topics: Colorectal cancer & Receptor. The author has an hindex of 17, co-authored 38 publications receiving 3064 citations.
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Journal ArticleDOI
E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer
Fabio Petrocca,Fabio Petrocca,Rosa Visone,Mariadele Rapazzotti Onelli,Manisha H. Shah,Milena S. Nicoloso,Ivana de Martino,Dimitrios Iliopoulos,Emanuela Pilozzi,Chang Gong Liu,Massimo Negrini,Luigi Cavazzini,Stefano Volinia,Stefano Volinia,Hansjuerg Alder,Luigi P. Ruco,Gustavo Baldassarre,Carlo M. Croce,Andrea Vecchione,Andrea Vecchione +19 more
TL;DR: In this article, the miR-106b-25 cluster, upregulated in a subset of human gastric tumors, is activated by E2F1 in parallel with its host gene, Mcm7.
E2F1-Regulated MicroRNAs Impair TGFb-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer
Fabio Petrocca,Rosa Visone,Mariadele Rapazzotti Onelli,Manisha H. Shah,Milena S. Nicoloso,Ivana De Martino,Dimitrios Iliopoulos,Emanuela Pilozzi,Chang Gong Liu,Massimo Negrini,Luigi Cavazzini,Stefano Volinia,Hansjuerg Alder,Luigi P. Ruco,Gustavo Baldassarre,Carlo M. Croce,Andrea Vecchione +16 more
TL;DR: Evidence is provided that the miR-106b-25 cluster, upregulated in a subset of human gastric tumors, is involved in E2F1 posttranscriptional regulation and may play a key role in the development of TGFbeta resistance in gastric cancer.
Journal ArticleDOI
Expression of P2X7 Receptor Increases In Vivo Tumor Growth
Elena Adinolfi,Lizzia Raffaghello,Anna Lisa Giuliani,Luigi Cavazzini,Marina Capece,Paola Chiozzi,Giovanna Bianchi,Guido Kroemer,Vito Pistoia,Francesco Di Virgilio +9 more
TL;DR: It is found that P2X7 exhibits significant growth-promoting effects in vivo, and immunohistochemistry revealed strong P2x7 positivity in several human cancers.
Journal ArticleDOI
Immunohistochemical Test for MLH1 and MSH2 Expression Predicts Clinical Outcome in Stage II and III Colorectal Cancer Patients
TL;DR: Immunohistochemical testing for MLH1/MSH2 expression provides useful prognostic information for the management of stage II and III colorectal cancer patients, and patients with MMRP-negative carcinomas demonstrated a marked reduction in the risk of cancer-related death with respect to patients withMMP-positive tumors.
Journal ArticleDOI
Elevated expression of A3 adenosine receptors in human colorectal cancer is reflected in peripheral blood cells.
Stefania Gessi,Elena Cattabriga,Arianna Avitabile,Roberta Gafà,Giovanni Lanza,Luigi Cavazzini,Nicoletta Bianchi,Roberto Gambari,Carlo V. Feo,Alberto Liboni,Sergio Gullini,Edward Leung,Stephen Maclennan,Pier Andrea Borea +13 more
TL;DR: This study provides the first evidence that A3 receptor plays a role in colon tumorigenesis and, more importantly, can potentially be used as a diagnostic marker or a therapeutic target for colon cancer.