Annalisa Pasini

TL;DR: The findings suggest that the beneficial effect on graft‐versus‐host disease induced by in vivo coinfusion with the graft of MSCs may be due to the activation of the immunomodulatory properties of M SCs by T cell– derived IFN‐γ.

TL;DR: This surgical procedure is a low-invasive therapeutic approach for resolving the late side effects of radiotherapy, and treatment with lipoaspirate transplantation is potentially extended to other forms of microangiopathies.

TL;DR: It is demonstrated that human BM‐derived MSCs expressed high levels of Toll‐like receptors (TLRs) 3 and 4, which are both functional, as shown by the ability of their ligands to induce nuclear factor κB (NF‐κB) activity, as well as the production of interleukin (IL)‐6, IL‐8, and CXCL10.

TL;DR: Data show that HB-EGF/HER-1 signaling is relevant to MSC biology, by regulating both proliferation and differentiation, in a dose-dependent fashion.

TL;DR: Results show that a MSC reservoir is present in tissues other than BM and fat, and that MSCs of different origin have similar neural differentiation potential, which provides new insights into BM-like tissue plasticity and may have important implications for future therapeutic interventions in chronic neuropathies.