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Annayya R. Aroor
Researcher at University of Missouri
Publications - 107
Citations - 5222
Annayya R. Aroor is an academic researcher from University of Missouri. The author has contributed to research in topics: Insulin resistance & Angiotensin II. The author has an hindex of 38, co-authored 101 publications receiving 4091 citations. Previous affiliations of Annayya R. Aroor include Veterans Health Administration.
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Journal ArticleDOI
The pathophysiology of hypertension in patients with obesity
TL;DR: The pathophysiology of obesity-related hypertension is especially relevant to premenopausal women with obesity and type 2 diabetes mellitus who are at high risk of developing arterial stiffness and endothelial dysfunction.
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MAP kinase signaling in diverse effects of ethanol.
TL;DR: Recent developments place MAPK in a pivotal position in relation to cellular actions of ethanol, and offer promising insights into the specificity of ethanol effects and pharmacological modulation of MAPK signaling.
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Endothelial cell senescence in aging-related vascular dysfunction.
TL;DR: A contemporary update on molecular mechanisms, pathophysiological events, as well functional changes in EC senescence and age-associated cardiovascular disease is provided.
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Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetes
Javad Habibi,Javad Habibi,Annayya R. Aroor,Annayya R. Aroor,James R. Sowers,Guanghong Jia,Guanghong Jia,Melvin R. Hayden,Mona Garro,Mona Garro,Brady J. Barron,Brady J. Barron,Eric Mayoux,R. Scott Rector,R. Scott Rector,Adam Whaley-Connell,Adam Whaley-Connell,Vincent G. DeMarco,Vincent G. DeMarco +18 more
TL;DR: EMPA improved glycemic indices along with diastolic relaxation, as well as SGK1/ENaC profibrosis signaling and associated interstitial fibrosis, all of which occurred in the absence of any changes in BP.
Journal ArticleDOI
Maladaptive immune and inflammatory pathways lead to cardiovascular insulin resistance.
Annayya R. Aroor,Annayya R. Aroor,Susan C. McKarns,Vincent G. DeMarco,Guanghong Jia,Guanghong Jia,James R. Sowers,James R. Sowers +7 more
TL;DR: New insights are provided into factors, such as, the renin-angiotensin-aldosterone system, sympathetic activation and incretin modulators and immune responses that mediate this inflammatory state in obesity and other conditions characterized by insulin resistance.