G
Guanghong Jia
Researcher at University of Missouri
Publications - 67
Citations - 4785
Guanghong Jia is an academic researcher from University of Missouri. The author has contributed to research in topics: Insulin resistance & Insulin. The author has an hindex of 27, co-authored 67 publications receiving 3138 citations. Previous affiliations of Guanghong Jia include Veterans Health Administration.
Papers
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Journal ArticleDOI
Diabetic Cardiomyopathy: An Update of Mechanisms Contributing to This Clinical Entity.
TL;DR: A contemporary view is provided of the instigators of diabetic cardiomyopathy, as well as mechanistically based strategies for the prevention and treatment of diabetic CARDIomyopathy.
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Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy
TL;DR: A surge in diabetic cardiomyopathy research is highlighted, current understanding of the molecular mechanisms underpinning this condition is summarized, and potential preventive and therapeutic strategies are explored.
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Diabetic cardiomyopathy: a hyperglycaemia- and insulin-resistance-induced heart disease
TL;DR: The current understanding of the pathophysiological mechanisms in diabetic cardiomyopathy is summarized, potential preventative and therapeutic strategies are explored and the relationships among insulin resistance/hyperinsulinaemia, hyperglycaemia and the development of cardiac dysfunction are reviewed.
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Endothelial cell senescence in aging-related vascular dysfunction.
TL;DR: A contemporary update on molecular mechanisms, pathophysiological events, as well functional changes in EC senescence and age-associated cardiovascular disease is provided.
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Sodium glucose transporter 2 (SGLT2) inhibition with empagliflozin improves cardiac diastolic function in a female rodent model of diabetes
Javad Habibi,Javad Habibi,Annayya R. Aroor,Annayya R. Aroor,James R. Sowers,Guanghong Jia,Guanghong Jia,Melvin R. Hayden,Mona Garro,Mona Garro,Brady J. Barron,Brady J. Barron,Eric Mayoux,R. Scott Rector,R. Scott Rector,Adam Whaley-Connell,Adam Whaley-Connell,Vincent G. DeMarco,Vincent G. DeMarco +18 more
TL;DR: EMPA improved glycemic indices along with diastolic relaxation, as well as SGK1/ENaC profibrosis signaling and associated interstitial fibrosis, all of which occurred in the absence of any changes in BP.