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Anne Laurençon
Researcher at Centre national de la recherche scientifique
Publications - 18
Citations - 1340
Anne Laurençon is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Drosophila melanogaster & Cilium. The author has an hindex of 13, co-authored 17 publications receiving 1263 citations. Previous affiliations of Anne Laurençon include University of Lyon & Claude Bernard University Lyon 1.
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The histone H3.3 chaperone HIRA is essential for chromatin assembly in the male pronucleus
Benjamin Loppin,Emilie Bonnefoy,Caroline Anselme,Anne Laurençon,Timothy L. Karr,Pierre Couble +5 more
TL;DR: It is shown that ssm is a point mutation in the Hira gene, thus demonstrating that the histone chaperone protein HIRA is required for nucleosome assembly during sperm nucleus decondensation, and that nucleosomes containing H3.3, and not H3, are specifically assembled in paternal Drosophila chromatin before the first round of DNA replication.
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The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition.
TL;DR: In this article, the authors show that embryos lacking Mei-41, a Drosophila homologue of the ATM tumor suppressor, fail to terminate syncytial division following mitosis 13, and degenerate without forming cells.
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Drosophila regulatory factor X is necessary for ciliated sensory neuron differentiation.
Raphaëlle Dubruille,Anne Laurençon,Camille Vandaele,Emiko Shishido,Madeleine Coulon-Bublex,Peter Swoboda,Pierre Couble,Maurice J. Kernan,Bénédicte Durand +8 more
TL;DR: Rfx is identified as an essential regulator of ciliated sensory neuron differentiation in Drosophila and its central role in sensory cilium differentiation is demonstrated.
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Transcriptional control of genes involved in ciliogenesis: a first step in making cilia.
Joëlle Thomas,Laurette Morlé,Fabien Soulavie,Anne Laurençon,Sébastien Sagnol,Bénédicte Durand +5 more
TL;DR: Different transcription factors playing specific roles in cilia biogenesis and physiology have also been discovered and all these factors are subject to complex regulation to allow for the dynamic and specific regulation of ciliogenesis in metazoans.
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Identification of novel regulatory factor X (RFX) target genes by comparative genomics in Drosophila species
Anne Laurençon,Raphaëlle Dubruille,Raphaëlle Dubruille,Evgeni Efimenko,Guillaume Grenier,Ryan Bissett,Ryan Bissett,Elisabeth Cortier,Vivien Rolland,Peter Swoboda,Bénédicte Durand +10 more
TL;DR: This work demonstrates the accuracy of the X-box screen and will be useful for the identification of candidate genes for human ciliopathies, as several human homologs of RFX target genes are known to be involved in diseases, such as Bardet-Biedl syndrome.