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Ody C. M. Sibon

Researcher at University Medical Center Groningen

Publications -  77
Citations -  4483

Ody C. M. Sibon is an academic researcher from University Medical Center Groningen. The author has contributed to research in topics: Coenzyme A & Centrosome. The author has an hindex of 33, co-authored 75 publications receiving 3970 citations. Previous affiliations of Ody C. M. Sibon include Stony Brook University & Utrecht University.

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Identification of heart rate–associated loci and their effects on cardiac conduction and rhythm disorders

Marcel den Hoed, +267 more
- 01 Jun 2013 - 
TL;DR: A 2-stage meta-analysis of genome-wide association studies in up to 181,171 individuals identified 14 new loci associated with heart rate and confirmed associations with all 7 previously established loci, providing fresh insights into the mechanisms regulating heart rate.
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DNA-replication checkpoint control at the Drosophila midblastula transition

TL;DR: This article showed that mutations in the grapes (grp) checkpoint 1 kinase homologue in Drosophila block the morphological and biochemical changes that accompany the midblastula transition, leading to a continuation of the maternal cell-cycle programme, and disrupt DNA-replication checkpoint control of cell cycle progression.
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Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex.

TL;DR: Biochemical and ultrastructural data presented here show that the telomeric DNA and TRF colocalize in individual, condensed structures in the nuclear matrix, consistent with the view that mammalian telomeres form nuclear matrix- associated, TRF-containing higher order complexes at dispersed sites throughout the nuclear volume.
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Polarised asymmetric inheritance of accumulated protein damage in higher eukaryotes

TL;DR: It is reported that cells that have formed aggresomes can undergo normal mitosis and the inheritance of protein aggregates during mitosis occurs with a fixed polarity indicative of a mechanism to preserve the long-lived progeny.
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De novo formation of centrosomes in vertebrate cells arrested during S phase

TL;DR: In this article, the authors show that when centrosomes are completely destroyed by laser microsurgery in CHO cells arrested in S phase by hydroxyurea, new centrosome form by de novo assembly.