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Annika Scheynius

Researcher at Karolinska Institutet

Publications -  218
Citations -  16576

Annika Scheynius is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Malassezia sympodialis & Immunoglobulin E. The author has an hindex of 62, co-authored 215 publications receiving 15284 citations. Previous affiliations of Annika Scheynius include Karolinska University Hospital & Boston Children's Hospital.

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Elevated levels of IgG and IgG4 to Malassezia allergens in atopic eczema patients with IgE reactivity to Malassezia.

TL;DR: Elevated serum IgG4 to M. sympodialis extract accompanies elevated serum IgE to the extract, which is further confirmed by the association between IgG/IgG4 and IgGE to recombinant Malassezia allergens.
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Zymosan suppresses leukotriene C4 synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors

TL;DR: A late PGE2‐mediated phosphoregulation of LTC4S during microbial exposure, which may contribute to resolution of inflammation, with implications for aspirin hypersensitivity, are suggested.
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Lifestyle and parental allergen sensitization are reflected in the intrauterine environment at gene expression level

TL;DR: This work has shown that lifestyle and parental allergen sensitization are reflected in the intrauterine environment at gene expression level at geneexpression level.
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Patients with psoriasis have elevated levels of serum eosinophil cationic protein and increased numbers of EG2 positive eosinophils in the duodenal stroma.

TL;DR: Psoriasis patients had significantly elevated serum levels of ECP even after exclusion of five of 37 sera which were Phadiatop positive, and the elevated serum ECP was not associated with the presence of IgA or IgG antibodies to gliadin.
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Elevated peripheral allergen-specific T cell response is crucial for a positive atopy patch test reaction.

TL;DR: Peripheral allergen-specific T helper 2 cell-mediated reactivity appears to be required for a positive APT reaction to M. sympodialis, and the diagnostic potential of measuring peripheral allerGEN- specific T cell responses should be considered in atopic eczema.