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Annika Scheynius

Researcher at Karolinska Institutet

Publications -  218
Citations -  16576

Annika Scheynius is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Malassezia sympodialis & Immunoglobulin E. The author has an hindex of 62, co-authored 215 publications receiving 15284 citations. Previous affiliations of Annika Scheynius include Karolinska University Hospital & Boston Children's Hospital.

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Truncated thioredoxin (Trx80) exerts unique mitogenic cytokine effects via a mechanism independent of thiol oxido-reductase activity.

TL;DR: Cysteine to serine mutants of Trx80 corresponding to the active site cysteines oftrx (Trx80SGPS) and to the structural cysteine at position 72 (trx80C72S) are engineered to further characterise Trx 80.
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No evidence for a placental microbiome in human pregnancies at term

TL;DR: No evidence to support the existence of a placental microbiome is found in a cross-sectional study comparing samples from two groups of full-term births using PCR amplification and sequencing techniques and bacterial culture experiments.
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Dendritic cells and fungi.

TL;DR: Fungi provide a powerful activation stimulus to dendritic cells, resulting in DC maturation with upregulation of co‐stimulatory molecules and production of cytokine patterns leading to different T cell responses, and the possibility of using ex vivo‐generated DCs as therapeutic tools for restoring anti‐fungal immunity is a challenge for the future.
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Truncated thioredoxin (Trx80) induces differentiation of human CD14 monocytes into a novel cell type (TAMs) via activation of the MAP kinases p38, ERK, and JNK

TL;DR: In this article, Trx80-activated monocytes (TAMs) were shown to induce differentiation of human CD14+ monocytes into a cell type not described previously.