Annika Scheynius

TL;DR: An aberrant expression of ICAM-1 and HLA-DR was found in the liver in both patients with EHBA and patients with Byler's disease, indicating that it is not merely an unspecific event secondary to cholestasis.

TL;DR: Evidence is provided that IL-18 is directly coupled to induction of self-reactive IgM and IgG antibody responses and recruitment of innate B2 B cells residing in the marginal zone of the spleen, and evidence that the B-cell activation occurs predominantly in splenic extrafollicular plasma cell foci and is regulated by natural killer T (NKT) cells that prevent formation of mature germinal centers.

TL;DR: The levels of small RNAs were not significantly differentially expressed between the two different pH conditions indicating that they are not influenced by the elevated pH level observed on the AE skin.

TL;DR: Mesoporous silica particles can be used as delivery vehicles with tunable adjuvant properties, which may be of importance for several medical applications, such as immune therapy and vaccination.

TL;DR: In a comparison of their ability to stimulate CD8+ T cells, it was found that the IL‐4/IL‐3 MDDCs were slightly more efficient than the conventionalMDDCs at inducing interferon (IFN)‐γ release in response to viral peptides.