A
Anoop Kumar
Researcher at University of Illinois at Chicago
Publications - 158
Citations - 2319
Anoop Kumar is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 23, co-authored 125 publications receiving 1616 citations. Previous affiliations of Anoop Kumar include Birla Institute of Technology, Mesra & Translational Health Science and Technology Institute.
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Journal ArticleDOI
Angiotensin II inhibits P-glycoprotein in intestinal epithelial cells.
Anoop Kumar,Shubha Priyamvada,Soni,Arivarasu Natarajan Anbazhagan,Tarunmeet Gujral,Ravinder K. Gill,Waddah A. Alrefai,Waddah A. Alrefai,Pradeep K. Dudeja,Pradeep K. Dudeja,Seema Saksena,Seema Saksena +11 more
TL;DR: P‐glycoprotein (Pgp/MDR1) plays a major role in intestinal homeostasis and Angiotensin II (Ang II), a peptide hormone predominantly expressed in the epithelial cells of the crypt‐villus junction of the intestine, has been shown to exert pro‐inflammatory effects in the gut.
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Hepatocyte nuclear factor 4α regulates the expression of intestinal epithelial Na+/H+ exchanger isoform 3
Saminathan Muthusamy,Jong Jin Jeong,Ming Cheng,Jessica A. Bonzo,Anoop Kumar,Frank J. Gonzalez,Alip Borthakur,Pradeep K. Dudeja,Pradeep K. Dudeja,Seema Saksena,Seema Saksena,Jaleh Malakooti +11 more
TL;DR: It is shown for the first time that hepatocyte nuclear factor 4α directly regulates NHE3 promoter activity and its basal expression in the intestine and represents an important and novel target for therapeutic intervention in IBD-associated diarrhea.
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Colonic delivery of vasoactive intestinal peptide nanomedicine alleviates colitis and shows promise as an oral capsule.
Dulari Jayawardena,Arivarasu Natarajan Anbazhagan,Shubha Priyamvada,Anoop Kumar,Anoop Kumar,Seema Saksena,Seema Saksena,Hayat Onyuksel,Pradeep K. Dudeja,Pradeep K. Dudeja +9 more
TL;DR: VIP-SSM is an effective nanomedicine formulation which appears to have potential for oral treatment of colitis in humans and in vitro release studies of a potential oral formulation are conducted.
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Risk Analysis of Lurasidone in Patients with Schizophrenia and Bipolar Depression.
Harika Modugula,Anoop Kumar +1 more
TL;DR: The causality assessment has shown a probable correlation of lurasidone with rabbit syndrome, hyper sexuality, restless leg syndrome, thrombocytopenia, oculogyric crisis and possible correlation with telogen effluvium.
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Downregulation of NHE-3 (SLC9A3) Expression by MicroRNAs in Intestinal Epithelial Cells.
Arivarasu Natarajan Anbazhagan,Shubha Priyamvada,Anoop Kumar,Dulari Jayawardena,Alip Borthakur,Ravinder K. Gill,Waddah A. Alrefai,Pradeep K. Dudeja,Seema Saksena +8 more
TL;DR: A novel mechanism for post transcriptional regulation of NHE-3 by miR-326 and -330-5p by translational repression is demonstrated and it is speculated that miR+ /H+ exchanger-3 dependent pathways may be involved in modulating N HE-3 expression under physiological and pathophysiological conditions.