Anthony P. Weetman

TL;DR: The revolution in molecular techniques has allowed dissection of the autoimmune response in a way impossible to imagine 10 yr ago, but there have been no really major improvements in the understanding of the immunogenetics of thyroid autoimmunity, equivalent to those made in type 1 diabetes mellitus.

TL;DR: Radiological and clinical markers of disease activity were significantly decreased for at least 18 months after treatment, however, a third of patients developed antibodies against the thyrotropin receptor and carbimazole-responsive autoimmune hyperthyroidism.

TL;DR: In this article, a genomewide association study was conducted to identify generalized vitiligo susceptibility loci, where 579,146 single-nucleotide polymorphisms (SNPs) were found in 1514 patients with generalized vitilligo who were of European-derived white ancestry and compared the genotypes with publicly available control genotypes from 2813 CEU persons.

TL;DR: It is demonstrated that leptin has a direct effect on the generation of an inflammatory response, and is of relevance when considering leptin therapy and may partly explain the relationship among leptin, proinflammatory cytokines, insulin resistance, and obesity.

TL;DR: A review of autoimmune thyroid disease will highlight the recent advances made in understanding the control of the autoimmune process particularly at pathogenetic and therapeutic levels and consider the current themes in autoimmunity in general.