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Antje Huefner
Researcher at University of Graz
Publications - 24
Citations - 348
Antje Huefner is an academic researcher from University of Graz. The author has contributed to research in topics: Abietic acid & Ailanthus excelsa. The author has an hindex of 9, co-authored 24 publications receiving 319 citations.
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Journal ArticleDOI
Mechanisms of Osteoclastogenesis Inhibition by a Novel Class of Biphenyl-Type Cannabinoid CB2 Receptor Inverse Agonists
Wolfgang Schuehly,Juan Manuel Viveros Paredes,Jonas Kleyer,Antje Huefner,Sharon Anavi-Goffer,Sharon Anavi-Goffer,Stefan Raduner,Karl-Heinz Altmann,Jürg Gertsch +8 more
TL;DR: The data show that CB(2) receptor-mediated cAMP formation, but not intracellular calcium, is crucially involved in the regulation of osteoclastogenesis, primarily by inhibiting macrophage chemotaxis and TNF-α expression.
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4'''-Acetylvitexin-2''-O-rhamnoside, isoorientin, orientin, and 8-methoxykaempferol-3-O-glucoside as markers for the differentiation of Crataegus monogyna and Crataegus pentagyna from Crataegus laevigata (Rosaceae)
TL;DR: The qualitative and quantitative flavonoid fingerprint of Crataegus monogyna and C. pentagyna is presented and laevigata offers an appropriate tool for additional differentiation from C.pentagyna and the main flavonoids 7, 8, and 12 could be proposed as markers for C.monogyna.
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Modulation of GABAA-Receptors by Honokiol and Derivatives: Subtype Selectivity and Structure–Activity Relationship
Barbara Taferner,Wolfgang Schuehly,Antje Huefner,Igor Baburin,Katharina Wiesner,Gerhard F. Ecker,Steffen Hering +6 more
TL;DR: 31 was most efficient on α(2)β(2)-receptors, suggesting a role of the acetamido group in subunit-dependent receptor modulation, and a model with an overall classification accuracy of 91% showed three hydrophobic regions, one acceptor and one donor region.
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NMR and Radical Scavenging Activities of Patuletin from Urtica urens. Against Aflatoxin B1
TL;DR: It is concluded that patuletin possesses an antioxidant activity and free radical scavenging effects in AFB1-treated rats that can be observed at a dose as low as 7.5 mg/kg b.w.
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Chemosystematic value of flavonoids from Crataegus x macrocarpa (Rosaceae) with special emphasis on (R)- and (S)-eriodictyol-7-O-glucuronide and luteolin-7-O-glucuronide.
TL;DR: The chemotaxonomic investigation of Crataegus x macrocarpa, a hybrid of C. laevigata and C. rhipidophylla, presents the qualitative and quantitative composition of its flavonoid pattern in relationship to its parent species for the first time.