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Anton F.P.M. de Goeij
Researcher at Maastricht University
Publications - 49
Citations - 4060
Anton F.P.M. de Goeij is an academic researcher from Maastricht University. The author has contributed to research in topics: Colorectal cancer & Diet and cancer. The author has an hindex of 33, co-authored 49 publications receiving 3825 citations. Previous affiliations of Anton F.P.M. de Goeij include Maastricht University Medical Centre.
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Journal ArticleDOI
Dietary folate intake and k‐ras mutations in sporadic colon and rectal cancer in the Netherlands Cohort Study
Mirian Brink,Matty P. Weijenberg,Anton F.P.M. de Goeij,Guido M.J.M. Roemen,Marjolein H.F.M. Lentjes,Adriaan P. de Bruïne,Manon van Engeland,R. Alexandra Goldbohm,Piet A. van den Brandt +8 more
TL;DR: Folate intake was associated with a decreased disease risk in men and was most pronounced for K‐ras mutated tumors, whereas an increased association was observed for women, and the effect of folate on rectal cancer risk is different for men and women and depends on the K‐ra mutation status of the tumor.
Journal ArticleDOI
Proteome analysis of human mesothelial cells during epithelial to mesenchymal transitions induced by shed menstrual effluent.
Ayşe Y. Demir,Ayşe Y. Demir,Hans Demol,Magda Puype,Anton F.P.M. de Goeij,Gerard A.J. Dunselman,Andreas Herrler,Johannes L.H. Evers,Joël Vandekerckhove,Patrick G. Groothuis +9 more
TL;DR: Using radiolabeling and proteomics, factors from menstrual effluent induce specific changes in the expression and phosphorylation status of structural, regulatory and metabolic proteins relevant to the complex process of EMT in mesothelial cells.
Journal ArticleDOI
Olfactomedin-4 Regulation by Estrogen in the Human Endometrium Requires Epidermal Growth Factor Signaling
Hellen Dassen,Chamindie Punyadeera,Bert Delvoux,Iris A. Schulkens,Claudia Marchetti,Rick Kamps,Jan P. G. Klomp,Fred Dijcks,Anton F.P.M. de Goeij,Thomas D'Hooghe,Cleophas M. Kyama,Antwan G. Ederveen,Gerard A.J. Dunselman,Patrick G. Groothuis,Andrea Romano +14 more
TL;DR: In this article, the authors examined the regulation and function of OLFM-4 in normal endometrium and in cases of endometriosis and endometrial cancer using the luciferase reporter under control of the Olfactomedin-4 promoter.
Journal ArticleDOI
Dietary Folate and APC Mutations in Sporadic Colorectal Cancer
Stefan de Vogel,Manon van Engeland,Margreet Lüchtenborg,Adriaan P. de Bruïne,Guido M.J.M. Roemen,Marjolein H.F.M. Lentjes,R. Alexandra Goldbohm,Piet A. van den Brandt,Anton F.P.M. de Goeij,Matty P. Weijenberg +9 more
TL;DR: Relatively high folate consumption reduced the risk ofAPC(-) colon tumors, but folate intake was positively associated with APC(+) colon tumors among men, which may indicate that folate enhances colorectal carcinogenesis through a distinct APC mutated pathway.
Journal ArticleDOI
Alcohol and the risk of colon and rectal cancer with mutations in the K-ras gene
TL;DR: Alcohol does not seem to be involved in predisposing to CRC through mutations in the K-ras gene, and specifically beer consumption is not associated with colon and rectal tumors harboring a G-->A mutation.