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Anton F.P.M. de Goeij
Researcher at Maastricht University
Publications - 49
Citations - 4060
Anton F.P.M. de Goeij is an academic researcher from Maastricht University. The author has contributed to research in topics: Colorectal cancer & Diet and cancer. The author has an hindex of 33, co-authored 49 publications receiving 3825 citations. Previous affiliations of Anton F.P.M. de Goeij include Maastricht University Medical Centre.
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Journal ArticleDOI
Fruits, Vegetables, and hMLH1 Protein–Deficient and –Proficient Colon Cancer: The Netherlands Cohort Study
Petra A. Wark,Matty P. Weijenberg,Pieter van 't Veer,Gerda van Wijhe,Margreet Lüchtenborg,Goos N.P. van Muijen,Anton F.P.M. de Goeij,R. Alexandra Goldbohm,Piet A. van den Brandt +8 more
TL;DR: It is indicated that an inverse association between consumption of fruits and colon cancer may be confined to the subgroup of tumors with a deficient mismatch repair system.
Journal ArticleDOI
Optimizing the APC gene mutation analysis in archival colorectal tumor tissue.
TL;DR: Critical steps in the methodology of mutation analysis on routinely fixed, paraffin-embedded samples have been evaluated, including extraction and purification of DNA, amplification of gene fragments in various sizes, and screening for mutations.
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APC mutations in human colorectal adenomas: analysis of the mutation cluster region with temperature gradient gel electrophoresis and clinicopathological features
TL;DR: It is concluded that an increased proportion of APC gene mutations were found in the adenomas showing clinicopathological features associated with increased proliferation but not with characteristics of malignant potential.
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Molecular characterization of soluble factors from human menstrual effluent that induce epithelial to mesenchymal transitions in mesothelial cells.
Ayşe Y. Demir,Ayşe Y. Demir,Patrick G. Groothuis,Gerard A.J. Dunselman,Leon J. Schurgers,Johannes L.H. Evers,Anton F.P.M. de Goeij +6 more
TL;DR: It is demonstrated that TNF-α is involved in EMT, whereas the other molecules are not, and when antibodies against TNF, α-enolase and haemoglobin are combined, EMT is almost completely inhibited.
Journal ArticleDOI
Alcohol consumption and distinct molecular pathways to colorectal cancer
Brenda Bongaerts,Anton F.P.M. de Goeij,Stefan de Vogel,Piet A. van den Brandt,R. Alexandra Goldbohm,Matty P. Weijenberg +5 more
TL;DR: It is indicated that a daily alcohol consumption of ≥ 30 g is associated with an increase in risk of CRC, independent of the presence or absence of the studied characteristics of different aetiological pathways.