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Antoni R. Slabas

Researcher at Durham University

Publications -  171
Citations -  7580

Antoni R. Slabas is an academic researcher from Durham University. The author has contributed to research in topics: Acyl carrier protein & Reductase. The author has an hindex of 49, co-authored 171 publications receiving 7194 citations. Previous affiliations of Antoni R. Slabas include University of London.

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Molecular basis of triclosan activity

TL;DR: It is found that triclosan acts as a site-directed, very potent inhibitor of the enzyme by mimicking its natural substrate.
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Identification of Arabidopsis salt and osmotic stress responsive proteins using two‐dimensional difference gel electrophoresis and mass spectrometry

TL;DR: It is demonstrated that NaCl causes a transient suppression of de novo protein synthesis, from which the cells recover within 4 h, which is a typical response of plant cells to salt and hyperosmotic stress.
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Proteomic analysis of the Arabidopsis thaliana cell wall.

TL;DR: Evidence for new proteins of unknown function whose existence had been predicted from genomic sequences are reported and an unexpected presence in the cell wall preparations of proteins whose known biochemical activity has never been associated with this compartment hitherto is observed.
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A mechanism of drug action revealed by structural studies of enoyl reductase.

TL;DR: Analysis of the structures of complexes of Escherichia coli ENR with nicotinamide adenine dinucleotide and either thienodiazaborine or benzodiazabadine revealed the formation of a covalent bond between the 2′ hydroxyl of the nicotinamia ribose and a boron atom in the drugs to generate a tight, noncovalently bound bisubstrate analog.
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Identification and functional expression of a type 2 acyl-CoA:diacylglycerol acyltransferase (DGAT2) in developing castor bean seeds which has high homology to the major triglyceride biosynthetic enzyme of fungi and animals.

TL;DR: In castor bean DGAT2 is more likely to play a major role in seed TAG biosynthesis than DGAT1, and expresses 18-fold more highly expressed in seeds than in leaves and shows temporal specific expression during seed development.