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Antonio Villaverde

Researcher at Autonomous University of Barcelona

Publications -  347
Citations -  11892

Antonio Villaverde is an academic researcher from Autonomous University of Barcelona. The author has contributed to research in topics: Inclusion bodies & Escherichia coli. The author has an hindex of 50, co-authored 324 publications receiving 10321 citations. Previous affiliations of Antonio Villaverde include Autonomous University of Madrid & Carlos III Health Institute.

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Microbial factories for recombinant pharmaceuticals

Neus Ferrer-Miralles, +4 more
- 24 Mar 2009 - 
TL;DR: The entering into the market of a progressively increasing number of protein drugs produced in non-microbial systems has not impaired the development of products obtained in microbial cells, proving the robustness of the microbial set of cellular systems developed for protein drug production.
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Protein quality in bacterial inclusion bodies

Salvador Ventura, +1 more
- 01 Apr 2006 - 
TL;DR: Recent data suggest that these protein aggregates might be a reservoir of alternative conformational states, their formation being no less specific than the acquisition of the native-state structure.
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Protein aggregation in recombinant bacteria: biological role of inclusion bodies

Antonio Villaverde, +1 more
- 01 Sep 2003 - 
TL;DR: A better understanding of protein aggregation in cell physiology could allow not only inclusion body formation to be minimized more efficiently for a higher soluble yield, but also to comprehend in detail the intricacy of cell mechanisms committed to handling the misfolding danger.
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Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview

Brigitte Gasser, +14 more
- 04 Apr 2008 - 
TL;DR: In this article, the main cellular players of this complex process are described for the most important cell factories used for biotechnological purposes, and the characterization of such adverse conditions and the elicited cell responses have permitted to better understand the physiology and molecular biology of conformational stress.
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Aggregation as bacterial inclusion bodies does not imply inactivation of enzymes and fluorescent proteins

Elena García-Fruitós, +7 more
- 12 Sep 2005 - 
TL;DR: It is shown that physiological aggregation in bacteria might only result in a moderate loss of biological activity and that inclusion bodies can be used in reaction mixtures for efficient catalysis.