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Aparecida S. Tanaka
Researcher at Federal University of São Paulo
Publications - 101
Citations - 2372
Aparecida S. Tanaka is an academic researcher from Federal University of São Paulo. The author has contributed to research in topics: Trypsin & Protease. The author has an hindex of 25, co-authored 98 publications receiving 2116 citations. Previous affiliations of Aparecida S. Tanaka include National Institute of Standards and Technology & Ludwig Maximilian University of Munich.
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Journal ArticleDOI
An insight into the transcriptome of the digestive tract of the bloodsucking bug, Rhodnius prolixus.
José M. C. Ribeiro,Fernando A. Genta,Marcos Henrique Ferreira Sorgine,Raquel Logullo,Rafael D. Mesquita,Gabriela O. Paiva-Silva,David Majerowicz,Marcelo N. Medeiros,Leonardo Koerich,Walter R. Terra,Clélia Ferreira,André C. Pimentel,Paulo Mascarello Bisch,Daniel Leite,Michelle M. P. Diniz,João Galan Júnior,Manuela Leal da Silva,Ricardo Nascimento Araújo,Ana Caroline P. Gandara,Sébastien Brosson,Didier Salmon,Sabrina Bousbata,Natalia González-Caballero,Ariel Mariano Silber,Michele Alves-Bezerra,Katia C. Gondim,Mário A.C. Silva-Neto,Georgia C. Atella,Helena Araujo,Felipe A. Dias,Carla Polycarpo,Raquel J. Vionette-Amaral,Patrícia Fampa,Ana C.A. Melo,Aparecida S. Tanaka,Carsten Balczun,Jose Henrique M. Oliveira,Renata L.S. Goncalves,Cristiano Lazoski,Rolando Rivera-Pomar,Luis Aníbal Diambra,Günter A. Schaub,Eloi S. Garcia,Patrícia Azambuja,Glória R.C. Braz,Pedro L. Oliveira +45 more
TL;DR: A new view of the triatomine digestive apparatus is presented and a role for MAP kinases, GTPases, and LKBP1/AMP kinases related to control of cell shape and polarity is suggested, possibly in connection with regulation of cell survival, response of pathogens and nutrients.
Journal ArticleDOI
Ixodidin, a novel antimicrobial peptide from the hemocytes of the cattle tick Boophilus microplus with inhibitory activity against serine proteinases.
Andréa Cristina Fogaça,Igor C. Almeida,Marcos N. Eberlin,Aparecida S. Tanaka,Philippe Bulet,Sirlei Daffre +5 more
TL;DR: The newly described AMP, designated ixodidin (derived from the Family Ixodidae), was found to exert proteolytic inhibitory activity against two exogenous serine proteinases, elastase and chymotrypsin.
Journal ArticleDOI
Infestin, a thrombin inhibitor presents in Triatoma infestans midgut, a Chagas' disease vector: gene cloning, expression and characterization of the inhibitor.
I. T. N. Campos,Rogerio Amino,Claudio A. M. Sampaio,Ennes A. Auerswald,T. Friedrich,H.-G. Lemaire,Sergio Schenkman,Aparecida S. Tanaka +7 more
TL;DR: This work describes the purification, gene cloning and expression of infestin, a thrombin inhibitor from midguts of Triatoma infestans, which encodes a multi non-classical Kazal-type serine protease inhibitor.
Journal ArticleDOI
BmTI antigens induce a bovine protective immune response against Boophilus microplus tick.
Renato Andreotti,Alberto Gomes,Kelly C Malavazi-Piza,Sergio D. Sasaki,Claudio A. M. Sampaio,Aparecida S. Tanaka +5 more
TL;DR: The preliminary results suggest that B. microplus serine proteinase inhibitors may play a role in the tick larvae fixation and feeding processes and the development of antibodies against BmTIs might impair the normal parasitism.
Journal ArticleDOI
Identification and characterization of a novel factor XIIa inhibitor in the hematophagous insect, Triatoma infestans (Hemiptera: Reduviidae).
TL;DR: The purification and characterization of recombinant infestins 3‐4 and 4 are described, which are potent factor XIIa inhibitors (K i=67 pM and 128 pM, respectively) and the first native factor XIa inhibitor from a hematophagous insect is identified.