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Rafael D. Mesquita
Researcher at Federal University of Rio de Janeiro
Publications - 37
Citations - 1127
Rafael D. Mesquita is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Rhodnius prolixus & Gene. The author has an hindex of 14, co-authored 33 publications receiving 899 citations. Previous affiliations of Rafael D. Mesquita include Universidade Tecnológica Federal do Paraná, Medianeira & National Institute of Standards and Technology.
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Journal ArticleDOI
Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection
Rafael D. Mesquita,Raquel J. Vionette-Amaral,Carl Lowenberger,Rolando Rivera-Pomar,Fernando A. Monteiro,Fernando A. Monteiro,Patrick Minx,John Spieth,A. Bernardo Carvalho,Francisco Panzera,Daniel Lawson,André Q. Torres,André Q. Torres,José M. C. Ribeiro,Marcos Henrique Ferreira Sorgine,Robert M. Waterhouse,Michael J. Montague,Fernando Abad-Franch,Michele Alves-Bezerra,Laurence Rodrigues do Amaral,Helena Araujo,Ricardo Nascimento Araújo,Ricardo Nascimento Araújo,L. Aravind,Georgia C. Atella,Patrícia Azambuja,Patrícia Azambuja,Mateus Berni,Paula R. Bittencourt-Cunha,Glória R.C. Braz,Gustavo M. Calderón-Fernández,Claudia M. A. Carareto,Mikkel B. Christensen,Igor Rodrigues da Costa,Samara G. da Costa,Marilvia Dansa,Carlos R. O. Daumas-Filho,Iron F. De-Paula,Felipe A. Dias,George Dimopoulos,Scott J. Emrich,Natalia Esponda-Behrens,Patrícia Fampa,Rita D. Fernandez-Medina,Rodrigo Nunes da Fonseca,Marcio Fontenele,Catrina Fronick,Lucinda Fulton,Ana Caroline P. Gandara,Eloi S. Garcia,Eloi S. Garcia,Fernando A. Genta,Fernando A. Genta,Gloria I. Giraldo-Calderón,Bruno Gomes,Bruno Gomes,Katia C. Gondim,Adriana Granzotto,Alessandra A. Guarneri,Alessandra A. Guarneri,Roderic Guigó,Myriam Harry,Daniel S.T. Hughes,Willy Jablonka,Emmanuelle Jacquin-Joly,M. Patricia Juárez,Leonardo Koerich,Angela B. Lange,Jose Manuel Latorre-Estivalis,Jose Manuel Latorre-Estivalis,Andrés Lavore,Gena G. Lawrence,Gena G. Lawrence,Cristiano Lazoski,Claudio R. Lazzari,Raphael R.S. Lopes,Marcelo G. Lorenzo,Marcelo G. Lorenzo,Magda D. Lugon,David Majerowicz,Paula L. Marcet,Marco Mariotti,Hatisaburo Masuda,Karyn Megy,Ana C.A. Melo,Fanis Missirlis,Theo Mota,Fernando G. Noriega,Marcela Nouzova,Rodrigo Dutra Nunes,Raquel L.L. Oliveira,Gilbert Oliveira-Silveira,Sheila Ons,Ian Orchard,Lucia Pagola,Gabriela O. Paiva-Silva,Agustina Pascual,Márcio G. Pavan,Nicolás Pedrini,Alexandre A. Peixoto,Alexandre A. Peixoto,Marcos H. Pereira,Marcos H. Pereira,Andrew Pike,Carla Polycarpo,Francisco Prosdocimi,Rodrigo Ribeiro-Rodrigues,Hugh M. Robertson,Ana Paula Salerno,Didier Salmon,Didac Santesmasses,Renata Schama,Renata Schama,Eloy S. Seabra-Junior,Lívia Silva-Cardoso,Mário A.C. Silva-Neto,Matheus Souza-Gomes,Marcos Sterkel,Mabel L. Taracena,Marta Tojo,Zhijian Jake Tu,Jose M. C. Tubio,Raul Ursic-Bedoya,Thiago M. Venancio,Thiago M. Venancio,Ana Beatriz Walter-Nuno,Derek Wilson,Wesley C. Warren,Richard K. Wilson,Erwin Huebner,Ellen M. Dotson,Pedro L. Oliveira +131 more
TL;DR: The first genome sequence of a nondipteran insect vector of an important human parasitic disease is described, which provides critical information on the physiology and evolution of this important vector species and should be instrumental for the development of innovative disease control methods.
Journal ArticleDOI
An insight into the transcriptome of the digestive tract of the bloodsucking bug, Rhodnius prolixus.
José M. C. Ribeiro,Fernando A. Genta,Marcos Henrique Ferreira Sorgine,Raquel Logullo,Rafael D. Mesquita,Gabriela O. Paiva-Silva,David Majerowicz,Marcelo N. Medeiros,Leonardo Koerich,Walter R. Terra,Clélia Ferreira,André C. Pimentel,Paulo Mascarello Bisch,Daniel Leite,Michelle M. P. Diniz,João Galan Júnior,Manuela Leal da Silva,Ricardo Nascimento Araújo,Ana Caroline P. Gandara,Sébastien Brosson,Didier Salmon,Sabrina Bousbata,Natalia González-Caballero,Ariel Mariano Silber,Michele Alves-Bezerra,Katia C. Gondim,Mário A.C. Silva-Neto,Georgia C. Atella,Helena Araujo,Felipe A. Dias,Carla Polycarpo,Raquel J. Vionette-Amaral,Patrícia Fampa,Ana C.A. Melo,Aparecida S. Tanaka,Carsten Balczun,Jose Henrique M. Oliveira,Renata L.S. Goncalves,Cristiano Lazoski,Rolando Rivera-Pomar,Luis Aníbal Diambra,Günter A. Schaub,Eloi S. Garcia,Patrícia Azambuja,Glória R.C. Braz,Pedro L. Oliveira +45 more
TL;DR: A new view of the triatomine digestive apparatus is presented and a role for MAP kinases, GTPases, and LKBP1/AMP kinases related to control of cell shape and polarity is suggested, possibly in connection with regulation of cell survival, response of pathogens and nutrients.
Journal ArticleDOI
Charting the Landscape of Tandem BRCT Domain–Mediated Protein Interactions
Nicholas T. Woods,Rafael D. Mesquita,Michael Sweet,Marcelo A. Carvalho,Xueli Li,Yun Liu,Huey Nguyen,C. Eric Thomas,Edwin S. Iversen,Sylvia M. Marsillac,Rachel Karchin,John M. Koomen,Alvaro N.A. Monteiro +12 more
TL;DR: Bioinformatics analysis of the BRCT protein-protein interaction network revealed biological processes and protein complexes that integrate the DDR with cell cycle regulation and transcription and signaling subnetworks that may aid in understanding the involvement of tBRCT in disease and DNA repair.
Journal ArticleDOI
Rhodnius prolixus supergene families of enzymes potentially associated with insecticide resistance
Renata Schama,Nicolás Pedrini,M. Patricia Juárez,David R. Nelson,André Q. Torres,Denise Valle,Rafael D. Mesquita +6 more
TL;DR: The identification of CCE, GST and CYP genes is of utmost importance for directing detoxification studies on triatomines that can help insecticide management strategies in control programs.
Journal ArticleDOI
Trypanosoma cruzi infection is enhanced by vector saliva through immunosuppressant mechanisms mediated by lysophosphatidylcholine.
Rafael D. Mesquita,Alan B. Carneiro,André Báfica,Felipe Gazos-Lopes,Christina Maeda Takiya,Thaïs Souto-Padrón,Danielle P. Vieira,Antonio Ferreira-Pereira,Igor C. Almeida,Rodrigo T. Figueiredo,Bárbara N. Porto,Marcelo T. Bozza,Aurélio V. Graça-Souza,Angela H. Lopes,Georgia C. Atella,Mário A.C. Silva-Neto +15 more
TL;DR: It is shown that vector saliva is a powerful inducer of cell chemotaxis and that a vector-derived lysophospholipid may act as an enhancing factor of Chagas disease.