Aparna Suvrathan

TL;DR: Findings from animal models on how stress-induced plasticity varies across different brain regions and thereby gives rise to the debilitating emotional and cognitive symptoms of stress-related psychiatric disorders are described.

TL;DR: It is reported that synaptic plasticity can itself be precisely tuned to the requirements of a learning task, and that the rules for induction of long-term and single-trial plasticity at parallel fiber-to-Purkinje cell synapses vary across cerebellar regions.

TL;DR: The results suggest that synaptic defects in the amygdala of knockout mice are still amenable to pharmacological interventions against mGluR5, albeit in a manner not envisioned in the original hippocampal framework.

TL;DR: In rats subjected to chronic immobilization stress, long-term potentiation and NMDA receptor-mediated synaptic responses are enhanced in principal neurons of the lateral amygdala, a brain area involved in fear memory formation, thereby creating an ideal neuronal substrate for affective disorders.

TL;DR: It is found that the intensity and duration of stress are critical in the development of depressive symptoms in male Wistar rats as tested in the forced-swim test and a need for closer examination of the ways in which stress-induced modulation of behaviour in the FST may be used and interpreted in future studies aimed at exploring connections between stress and depression.