A
Ar Bianco
Researcher at University of Naples Federico II
Publications - 140
Citations - 4969
Ar Bianco is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Cancer & Cell growth. The author has an hindex of 34, co-authored 135 publications receiving 4893 citations.
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Journal Article
Antitumor Effect and Potentiation of Cytotoxic Drugs Activity in Human Cancer Cells by ZD-1839 (Iressa), an Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor
Fortunato Ciardiello,Rosa Caputo,Roberto Bianco,Damiano,G Pomatico,De Placido S,Ar Bianco,Giampaolo Tortora +7 more
TL;DR: The antitumor effect of this EGFR-selective tyrosine kinase inhibitor ZD-1839 is demonstrated and a rationale for its clinical evaluation in combination with cytotoxic drugs is provided.
Journal ArticleDOI
c-erb B2 overexpression decreases the benefit of adjuvant tamoxifen in early-stage breast cancer without axillary lymph node metastases.
Chiara Carlomagno,Francesco Perrone,C. Gallo,M. De Laurentiis,Rossella Lauria,Alessandro Morabito,Guido Pettinato,Luigi Panico,A. D'Antonio,Ar Bianco,S. De Placido +10 more
TL;DR: In early-stage breast cancer patients, overexpression of c-erbB2 is a marker of lack of efficacy of adjuvant tamoxifen, and the role of each prognostic variable and their independent effect were studied using the Cox model.
Journal Article
Antiangiogenic and antitumor activity of anti-epidermal growth factor receptor C225 monoclonal antibody in combination with vascular endothelial growth factor antisense oligonucleotide in human GEO colon cancer cells.
Fortunato Ciardiello,Roberto Bianco,Vincenzo Damiano,G. Fontanini,Rosa Caputo,G Pomatico,S. De Placido,Ar Bianco,John Mendelsohn,Giampaolo Tortora +9 more
TL;DR: A significant potentiation in inhibition of VEGF expression and little or no microvessels were observed in GEO tumors after the combined treatment with the two agents after the antiangiogenic and antitumor activity of monoclonal antibody C225.
Journal Article
Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely resected stage I-IIIA non-small-cell lung cancer: amphiregulin and microvessel count are independent prognostic indicators of survival.
Gabriella Fontanini,M. De Laurentiis,S Vignati,S. Chine,Marco Lucchi,V Silvestri,Alfredo Mussi,S. De Placido,Giampaolo Tortora,Ar Bianco,William J. Gullick,Carlo Alberto Angeletti,Generoso Bevilacqua,Fortunato Ciardiello +13 more
TL;DR: Evaluation of neoangiogenesis and of certain growth factors, such as AR, can be useful in addition to conventional pathological staging to select high-risk NSCLC patients who may benefit from post-surgical systemic therapies.
Journal ArticleDOI
A phase II study of biweekly oxaliplatin plus infusional 5-fluorouracil and folinic acid (FOLFOX-4) as first-line treatment of advanced gastric cancer patients
F. De Vita,Michele Orditura,Elide Matano,Roberto Bianco,Chiara Carlomagno,S Infusino,Vincenzo Damiano,E Simeone,M. R. Diadema,Eva Lieto,Paolo Castellano,Stefano Pepe,S. De Placido,Gennaro Galizia,N. Di Martino,Fortunato Ciardiello,Giuseppe Catalano,Ar Bianco +17 more
TL;DR: Responsibility rate (RR), TTP and OS were comparable with those of other oxaliplatin-based regimens, suggesting a role for this combination in gastric cancer.