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Arduino A. Mangoni
Researcher at Flinders Medical Centre
Publications - 397
Citations - 10350
Arduino A. Mangoni is an academic researcher from Flinders Medical Centre. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 42, co-authored 348 publications receiving 7835 citations. Previous affiliations of Arduino A. Mangoni include University of Cambridge & King's College London.
Papers
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Journal ArticleDOI
Pharmacokinetic Characterization of the DDAH1 Inhibitors ZST316 and ZST152 in Mice Using a HPLC-MS/MS Method
Arduino A. Mangoni,Tommaso Ceruti,Roberta Frapolli,Massimo Russo,Stefania Fichera,Massimo Zucchetti,Sara Tommasi +6 more
TL;DR: ZST316 has a favorable pharmacokinetic profile, following intraperitoneal treatment with the more potent DDAH1 inhibitor, ZST316 (30 mg/Kg/day for three weeks), the bioavailability was 59% and no accumulation was observed.
Journal ArticleDOI
Non-steroidal anti-inflammatory drugs and atherothrombotic risk in older patients: where do we stand?
TL;DR: Issues are discussed together with a proposed mechanism to explain the results of recent studies demonstrating a relatively low atherothrombotic risk associated with NSAIDs in older patients and Suggestions for future research directions are provided.
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Prevalence and risk factors of moderate to severe hepatic steatosis in patients with rheumatoid arthritis: an ultrasonography cross-sectional case-control study.
Gian Luca Erre,Floriana Castagna,Assunta Sauchella,Pierluigi Meloni,Arduino A. Mangoni,Giuseppina Farina,Richard J. Woodman,Maria Pina Dore,Gianpaolo Vidili +8 more
TL;DR: In this article, the independent association between hepatic steatosis and rheumatoid arthritis was poorly defined, and the presence of moderate to severe steats was assessed, using liver ultrasonography.
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Psychotropics, Environmental Temperature, and Hospital Outcomes in Older Medical Patients.
TL;DR: Psychotropic use on admission, particularly antipsychotics, predicted hospital LOS, but not mortality, in older medical patients, particularly those older than 80 years, during normal environmental temperature, but there was no effect of psychotropics on LOS during extreme heat.
Journal ArticleDOI
Overexpression of dimethylarginine dimethylaminohydrolase 1 protects from angiotensin II-induced cardiac hypertrophy and vascular remodeling.
Irakli Kopaliani,Natalia Jarzebska,Silke Billoff,Anne Kolouschek,Jens Martens-Lobenhoffer,Stefan R. Bornstein,Stefanie M. Bode-Böger,Vinitha Nair Ragavan,Vinitha Nair Ragavan,Norbert Weiss,Arduino A. Mangoni,Andreas Deussen,Roman N. Rodionov +12 more
TL;DR: In this article, the role of dimethylarginine dimethylaminohydrolase 1 (DDAH1), an enzyme hydrolyzing ADMA, in prevention of cardiovascular remodeling during hypertension was investigated.