A
Ari M. Ferro
Researcher at University of California, San Francisco
Publications - 4
Citations - 150
Ari M. Ferro is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Adenosine & NAD+ kinase. The author has an hindex of 4, co-authored 4 publications receiving 147 citations.
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Covalent modification of proteins by metabolites of NAD
TL;DR: It is proposed that high turnover of cellular NAD+ is the source of aldehydic metabolites which may regulate macromolecular metabolism by covalent modification of nuclear proteins, whereas polyamines serve as modulators of this control cycle.
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Structure of a poly (adenosine diphosphoribose) monomer: 2'-(5"-hosphoribosyl)-5'-adenosine monophosphate
TL;DR: No evidence was found for heterogeneity in either the site of attachment or configuration of the linkage in the 2'-(5"-phosphoribosyl)-5'-AMP, and comparison of the coupling constants and the chemical shifts of the ribose hydroxyl protons of 2'-ribosyl adenosine with the model compounds establishes an alpha (1" leads to 2') glycosidic linkage inThe monomer.
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Analysis of larger than tetrameric poly(adenosine diphosphoribose) by a radioimmunoassay in nuclei separated in organic solvents
TL;DR: A membrane binding assay was developed, and its specificity determined for the detection of (adenosine diphosphoribose)ngreater than4 in organs, and the method is suitable for the study of the variation of the polymer content of nuclei.
Journal ArticleDOI
Macromolecular derivatives of NAD+ in heart nuclei: poly adenosine diphosphoribose and adenosine diphosphoribose proteins.
Ari M. Ferro,Ernest Kun +1 more
TL;DR: The polymer poly (ADP-R) was identified in both nuclear systems by isolation, digestion with snake venom phosphodiesterase and chromatographic separation of phosphoribosyl-AMP and AMP.