Arie Katz

TL;DR: It is concluded that QUICKI is an index of insulin sensitivity obtained from a fasting blood sample that may be useful for clinical research.

TL;DR: Dose concentration studies of vitamin C in healthy people showed a sigmoidal relationship between oral dose and plasma and tissue vitamin C concentrations, so optimal dosing is critical to intervention studies using vitamin C.

TL;DR: It is reported here that intravenous doses can produce plasma concentrations 30- to 70-fold higher than the maximum tolerated oral doses, and the role of vitamin C in cancer treatment should be reexamined, and insights from vitamin C pharmacokinetics can guide its clinical use.

TL;DR: The test characteristics of the logarithmic transformation of the homeostasis model assessment and the Quantitative Insulin Sensitivity Check Index are superior to other simple indices of insulin sensitivity and helps explain their excellent correlations with formal measures both at baseline and with changes in insulin sensitivity.

TL;DR: Findings suggest that in the skeletal muscle circulation, insulin stimulates both ET-1 and NO activity, an imbalance between the release of these 2 substances may be involved in the pathophysiology of hypertension and atherosclerosis in insulin-resistant states associated with endothelial dysfunction.