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Yaohui Wang
Researcher at National Institutes of Health
Publications - 40
Citations - 7257
Yaohui Wang is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Vitamin C & Ascorbic acid. The author has an hindex of 22, co-authored 35 publications receiving 6532 citations.
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Journal ArticleDOI
Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention
Sebastian J. Padayatty,Arie Katz,Yaohui Wang,Peter Eck,Oran Kwon,Je-Hyuk Lee,Shenglin Chen,Christopher Corpe,Anand Dutta,Sudhir K. Dutta,Mark Levine +10 more
TL;DR: Dose concentration studies of vitamin C in healthy people showed a sigmoidal relationship between oral dose and plasma and tissue vitamin C concentrations, so optimal dosing is critical to intervention studies using vitamin C.
Journal ArticleDOI
Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance.
Mark Levine,Cathy Conry-Cantilena,Yaohui Wang,Richard W. Welch,P Washko,K R Dhariwal,Jae B. Park,Alexander Lazarev,James F. Graumlich,Jean King,Louis R. Cantilena +10 more
TL;DR: The current RDA of 60 mg daily should be increased to 200 mg daily, which can be obtained from fruits and vegetables, and safe doses of vitamin C are less than 1000mg daily, and vitamin C daily doses above 400 mg have no evident value.
Journal ArticleDOI
Vitamin C Pharmacokinetics: Implications for Oral and Intravenous Use
Sebastian J. Padayatty,He Sun,Yaohui Wang,Hugh D. Riordan,Stephen M. Hewitt,Arie Katz,Robert Wesley,Mark Levine +7 more
TL;DR: It is reported here that intravenous doses can produce plasma concentrations 30- to 70-fold higher than the maximum tolerated oral doses, and the role of vitamin C in cancer treatment should be reexamined, and insights from vitamin C pharmacokinetics can guide its clinical use.
Journal ArticleDOI
Criteria and recommendations for vitamin C intake.
TL;DR: The tolerable upper intake level, the highest daily level of nutrient intake that does not pose risk or adverse health effects to almost all individuals in the population, is proposed to be less than 1 g of vitamin C daily.
Journal ArticleDOI
A new recommended dietary allowance of vitamin C for healthy young women
TL;DR: Results of a depletion–repletion study with healthy young women hospitalized for 186 +/− 28 days, using vitamin C doses of 30–2,500 mg daily indicate that the Recommended Dietary Allowance for young women should be increased to 90 mg daily.