Ariel A. Szklanny

TL;DR: Implantation of tropoelastin-treated scaffolds into mouse abdominal muscle resulted in enhanced perfusion of the penetrating vasculature and improved integration, pointing to the great potential of these combined materials in promoting the vascularization of implanted engineered constructs, which can be further exploited in the fabrication of clinically relevant engineered tissues.

TL;DR: In this article, a combination of millimetric vessel-like scaffolds and 3D bioprinted vascularized tissues interconnect, creating fully engineered hierarchical vascular constructs for implantation.

TL;DR: The oriented scaffold was shown to guide regenerating axons to linear conformations and support growth of induced pluripotent stem cell-derived neurons in vitro and in vivo in a model of spinal cord injury and may advance the field of nerve regeneration.

TL;DR: Highly vascularized DPSC‐embedded constructs bear angiogenic and neurotrophic potentials, capable of augmenting and modulating SCI repair, and demonstrate substantial regenerated vessels, more significantly in the sensory tract regions, which correlates with behavioral recovery following prevascularization treatment.

TL;DR: New insight is provided regarding vessel sprouting decisions that should be considered when designing scaffolds for vascularized engineered tissues, especially within 3D environments.