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Ariel Y. Deutch
Researcher at Vanderbilt University Medical Center
Publications - 163
Citations - 17012
Ariel Y. Deutch is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Dopamine & Striatum. The author has an hindex of 67, co-authored 162 publications receiving 16352 citations. Previous affiliations of Ariel Y. Deutch include United States Department of Veterans Affairs & Vanderbilt University.
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Topographical organization of the efferent projections of the medial prefrontal cortex in the rat: An anterograde tract-tracing study with Phaseolus vulgaris leucoagglutinin
TL;DR: The purpose of the present investigation was to examine the topographical organization of efferent projections from the cytoarchitectonic divisions of the mPFC (the medial precentral, dorsal anterior cingulate and prelimbic cortices) to determine whether the efferents from different regions within the prelimbics were organized topographically.
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The patterns of afferent innervation of the core and shell in the “Accumbens” part of the rat ventral striatum: Immunohistochemical detection of retrogradely transported fluoro‐gold
TL;DR: Immunohistochemical detection of retrogradely transported Fluoro‐Gold was carried out following iontophoretic injections intended to involve selectively one of the subterritories, revealing that a number of cortical afferents of the medial shell and core originate in separate areas.
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Selective elimination of glutamatergic synapses on striatopallidal neurons in Parkinson disease models
Michelle Day,Zhongfeng Wang,Jun B. Ding,Xinhai An,Cali A. Ingham,Andrew F Shering,David L. Wokosin,Ema Ilijic,Zhuoxin Sun,Allan R. Sampson,Enrico Mugnaini,Ariel Y. Deutch,Susan R. Sesack,Gordon W. Arbuthnott,D. James Surmeier +14 more
TL;DR: Using multiphoton imaging, it is shown that dopamine depletion leads to a rapid and profound loss of spines and glutamatergic synapses on striatopallidal MSNs but not on neighboring striatonigral MSNs, triggered by a new mechanism—dysregulation of intraspine Cav1.3 L-type Ca2+ channels.
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Psychobiologic Mechanisms of Posttraumatic Stress Disorder
TL;DR: Preclinical investigations of the effects of stress on learning and memory processes suggest that fear conditioning, behavioral sensitization, and a failure of extinction may be important in the persistence and reexperiencing of traumatic memories and stressor sensitivity.
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Anatomical substrates of orexin-dopamine interactions: lateral hypothalamic projections to the ventral tegmental area.
James R. Fadel,Ariel Y. Deutch +1 more
TL;DR: It is concluded that the lateral hypothalamic/perifornical projection represents an anatomical substrate by which interoceptive-related signals may influence forebrain dopamine function.