A
Ariella Coler-Reilly
Researcher at St. Marianna University School of Medicine
Publications - 33
Citations - 1145
Ariella Coler-Reilly is an academic researcher from St. Marianna University School of Medicine. The author has contributed to research in topics: Tropical spastic paraparesis & Myelopathy. The author has an hindex of 13, co-authored 28 publications receiving 741 citations. Previous affiliations of Ariella Coler-Reilly include Washington University in St. Louis.
Papers
More filters
Journal ArticleDOI
The complement system in COVID-19: friend and foe?
Anuja Java,Anthony J. Apicelli,M. Kathryn Liszewski,Ariella Coler-Reilly,John P. Atkinson,Alfred H.J. Kim,Hrishikesh S. Kulkarni +6 more
TL;DR: It is proposed that the combined effects of complement activation, dysregulated neutrophilia, endothelial injury, and hypercoagulability appear to be intertwined to drive the severe features of COVID-19 and create a basis for clinical trials of complement inhibitors in life-threatening illness.
Journal ArticleDOI
Hope on the Horizon: Novel Fungal Treatments in Development
TL;DR: This review focuses on novel therapies in clinical development, including drugs and a device that have novel mechanisms of action to overcome resistance, and some offer new formulations providing distinct advantages over current therapies to improve safety profiles and reduce interactions.
Journal ArticleDOI
HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells
Natsumi Araya,Tomoo Sato,Hitoshi Ando,Utano Tomaru,Mari Yoshida,Ariella Coler-Reilly,Naoko Yagishita,Junji Yamauchi,Atsuhiko Hasegawa,Mari Kannagi,Yasuhiro Hasegawa,Katsunori Takahashi,Yasuo Kunitomo,Yuetsu Tanaka,Toshihiro Nakajima,Kusuki Nishioka,Atae Utsunomiya,Steven Jacobson,Yoshihisa Yamano +18 more
TL;DR: It is demonstrated that Tax, in cooperation with specificity protein 1 (Sp1), boosts expression of the Th1 master regulator T box transcription factor (T-bet) and consequently promotes production of IFN-γ.
Journal ArticleDOI
CSF CXCL10, CXCL9, and Neopterin as Candidate Prognostic Biomarkers for HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis
Tomoo Sato,Ariella Coler-Reilly,Atae Utsunomiya,Natsumi Araya,Naoko Yagishita,Hitoshi Ando,Junji Yamauchi,Eisuke Inoue,Takahiko Ueno,Yasuhiro Hasegawa,Kusuki Nishioka,Toshihiro Nakajima,Toshihiro Nakajima,Steven Jacobson,Shuji Izumo,Yoshihisa Yamano +15 more
TL;DR: The CSF levels of chemokine (C-X-C motif) ligand 10 (CXCL10), CXCL9, and neopterin were well-correlated with disease progression, better even than HTLV-1 proviral load in PBMCs.
Journal ArticleDOI
Positive feedback loop via astrocytes causes chronic inflammation in virus-associated myelopathy
Hitoshi Ando,Tomoo Sato,Utano Tomaru,Mari Yoshida,Atae Utsunomiya,Junji Yamauchi,Natsumi Araya,Naoko Yagishita,Ariella Coler-Reilly,Yukiko Shimizu,Kazuo Yudoh,Yasuhiro Hasegawa,Kusuki Nishioka,Toshihiro Nakajima,Steven Jacobson,Yoshihisa Yamano +15 more
TL;DR: It is inferred that human T-lymphotropic virus type 1-infected cells in the central nervous system produce IFN-γ that induces astrocytes to secrete CXCL10, which recruits more infected cells to the area via CXCR3, constituting a T helpertype 1-centric positive feedback loop that results in chronic inflammation.