Aroni Chatterjee

TL;DR: Molecular docking studies using 10 potential naturally occurring compounds against the SARS-CoV-2 spike protein and compared their affinity with an FDA approved repurposed drug hydroxychloroquine revealed that these molecules bind with the hACE2-S complex with low binding free energy, and ADME analysis suggested that they consist of drug-likeness property, which may be further explored as anti-SARS- CoV- 2 agents.

TL;DR: These flavonoid and non-flavonoid moieties have significantly high binding affinity for the two main important domains of the spike protein which is responsible for the attachment and internalization of the virus in the host cell and their binding affinities are much higher compared to that of HCQ.

TL;DR: Mesenchymal stem cell therapy offers a promising approach towards mitigating the delirious effects of the infection in the COVID-19 patients, and has shown to reduce the expression of pro-inflammatory cytokines as well as repair of damaged tissues in COIDs patients.

TL;DR: This review mainly focuses on various nucleic acid-based biologically active molecules and their therapeutic potentials in developing vaccines for SARS-CoV-2.

TL;DR: Pyrimidine derivative AP-NP may be explored as an effective inhibitor for hACE2-S complex and in vitro and in vivo studies will strengthen the use of these inhibitors as suitable drug candidates against SARS-COV-2.