Arpi Nazarian

TL;DR: It is shown that matrices carrying the tethered homologs of natural phosphoinositides can be used to capture and display multiple phosphoinoskeleton-dependent rearrangements in the cell cytoskeleton and cell shape.

TL;DR: This paper showed that the exosome co-purifies with the RNA polymerase II elongation factor Spt6 (dSpt6) during normal development and is strongly recruited to heat-shock loci on polytene chromosomes.

TL;DR: It is shown that Drosophila Spt6 co-purifies with the exosome, a complex of 3′ to 5′ exoribonucleases that is implicated in the processing of structural RNA and in the degradation of improperly processed pre-mRNA.

TL;DR: It is established that heterogeneous fatty acylation is a widespread occurrence that serves to regulate signal transduction by membrane-bound proteins and that the nature of the attached fatty acid influences raft-mediated sign transduction.

TL;DR: It is shown here that mutations in the evolutionary conserved regions result in a more general loss of function, and these findings provide new insights into the antibacterial mechanism of a unique group of peptides and perhaps, by extension, for distant mammalian relatives such as PR-39.