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Arthur J. Cronin
Researcher at Pennsylvania State University
Publications - 14
Citations - 456
Arthur J. Cronin is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Melatonin & Remifentanil. The author has an hindex of 8, co-authored 14 publications receiving 410 citations. Previous affiliations of Arthur J. Cronin include Penn State Milton S. Hershey Medical Center.
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Postoperative sleep disturbance: influences of opioids and pain in humans.
TL;DR: Postoperative patients suffer a profound sleep disturbance even when opioids are avoided and pain is well controlled, and there was no statistically significant association between pain score and any polysomnographically defined stage.
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Melatonin secretion after surgery
TL;DR: Nocturnal concentrations of melatonin were significantly lower on the first than on the second or third nights after surgery, raising the possibility that melatonin suppression and associated sleep disturbance might be prevented by melatonin replacement.
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Propofol suppresses the cortical somatosensory evoked potential in rats.
Helene G. Logginidou,Bai Han Li,De Pei Li,Jeffrey S. Lohmann,H. Gregg Schuler,Nicole A. DiVittore,Sarah Kreiser,Arthur J. Cronin +7 more
TL;DR: Propofol significantly depressed the SEP amplitude and prolonged the latency at infusion rates of 40 mg · kg−1 · h−1 and more, suggesting that even at large doses, propofol and remifentanil provide adequate conditions for SEP monitoring.
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Preservation of the cortical somatosensory-evoked potential during dexmedetomidine infusion in rats.
TL;DR: It is demonstrated that dexmedetomidine maintains technically adequate conditions for SEP monitoring in rats and provides support for future studies of the effect of dexmedETomidine on SEP Monitoring in humans.
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Remifentanil inhibits rapid eye movement sleep but not the nocturnal melatonin surge in humans.
Christopher P. Bonafide,Natalie Aucutt-Walter,Nicole A. DiVittore,Tonya S. King,Edward O. Bixler,Arthur J. Cronin +5 more
TL;DR: An overnight constant infusion of remifentanil inhibits rapid eye movement sleep without suppressing the nocturnal melatonin surge, and the hypothesis that opioid-induced sleep disturbance is caused by a circadian pacemaker disturbance is tested, reflected by suppressedNocturnal plasma concentration of melatonin.