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Astrid Nehlig
Researcher at French Institute of Health and Medical Research
Publications - 205
Citations - 10071
Astrid Nehlig is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Epilepsy & Status epilepticus. The author has an hindex of 51, co-authored 199 publications receiving 9448 citations. Previous affiliations of Astrid Nehlig include Paris Descartes University.
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Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects.
TL;DR: Caffeine is the most widely consumed central-nervous-system stimulant as discussed by the authors, however, its psychostimulant action on man is often subtle and not very easy to detect.
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Are we dependent upon coffee and caffeine? A review on human and animal data.
TL;DR: It appears that although caffeine fulfils some of the criteria for drug dependence and shares with amphetamines and cocaine a certain specificity of action on the cerebral dopaminergic system, the methylxanthine does not act on the dopamine structures related to reward, motivation and addiction.
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Recurrent seizures and hippocampal sclerosis following intrahippocampal kainate injection in adult mice: electroencephalography, histopathology and synaptic reorganization similar to mesial temporal lobe epilepsy.
Viviane Bouilleret,Viviane Bouilleret,V Ridoux,Antoine Depaulis,Christian Marescaux,Astrid Nehlig +5 more
TL;DR: The data described describe the first histological, electrophysiological and behavioural evidence suggesting that discrete excitotoxic lesions of the hippocampus in mice can be used as an isomorphic model of mesial temporal lobe epilepsy.
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Is caffeine a cognitive enhancer
TL;DR: It appears that caffeine cannot be considered a ;pure' cognitive enhancer, as its indirect action on arousal, mood and concentration contributes in large part to its cognitive enhancing properties.