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Antoine Depaulis
Researcher at French Institute of Health and Medical Research
Publications - 153
Citations - 12900
Antoine Depaulis is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Epilepsy & Hippocampal formation. The author has an hindex of 63, co-authored 148 publications receiving 12273 citations. Previous affiliations of Antoine Depaulis include Centre national de la recherche scientifique & University of California, Los Angeles.
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Journal ArticleDOI
Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors.
Ja Hyun Baik,Roberto Picetti,Adolfo Saiardi,G. Thiriet,Andrée Dierich,Antoine Depaulis,Marianne Le Meur,Emiliana Borrelli +7 more
TL;DR: This study shows that D2 receptors have a key role in the dopaminergic control of nervous function, using homologous recombination to generate D2-receptor-deficient mice, which have therapeutic potential as a model for investigating and correcting dysfunctions of the dopamine system.
Journal ArticleDOI
Pathophysiological mechanisms of genetic absence epilepsy in the rat
TL;DR: In this article, a review summarizes data obtained on the neurophysiological and neurochemical mechanisms of absence seizures with special emphasis on the Genetic Absence Epilepsy Rats from Strasbourg (GAERS).
Journal ArticleDOI
Identifying neural drivers with functional MRI: an electrophysiological validation.
Olivier David,Isabelle Guillemain,Sandrine Saillet,Sebastien Reyt,Colin Deransart,Christoph Segebarth,Antoine Depaulis +6 more
TL;DR: The first experimental substantiation of the theoretical possibility to improve interregional coupling estimation from hidden neural states of fMRI is provided, which has important implications for future studies on brain connectivity using functional neuroimaging.
Book ChapterDOI
Genetic absence epilepsy in rats from Strasbourg--a review.
TL;DR: Neurophysiological, behavioural, pharmacological and genetic studies demonstrate that spontaneous SWD in GAERS fulfill all the requirements for an experimental model of absence epilepsy.
Journal ArticleDOI
Recurrent seizures and hippocampal sclerosis following intrahippocampal kainate injection in adult mice: electroencephalography, histopathology and synaptic reorganization similar to mesial temporal lobe epilepsy.
Viviane Bouilleret,Viviane Bouilleret,V Ridoux,Antoine Depaulis,Christian Marescaux,Astrid Nehlig +5 more
TL;DR: The data described describe the first histological, electrophysiological and behavioural evidence suggesting that discrete excitotoxic lesions of the hippocampus in mice can be used as an isomorphic model of mesial temporal lobe epilepsy.