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Atif Saghir

Researcher at University of Birmingham

Publications -  10
Citations -  172

Atif Saghir is an academic researcher from University of Birmingham. The author has contributed to research in topics: Arthritis & PDPN. The author has an hindex of 5, co-authored 10 publications receiving 149 citations. Previous affiliations of Atif Saghir include Queen Elizabeth Hospital Birmingham.

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Journal ArticleDOI

The response to testosterone undecanoate in men with type 2 diabetes is dependent on achieving threshold serum levels (the BLAST study).

TL;DR: This is the first double‐blind placebo‐controlled study conducted exclusively in a male type 2 diabetes population to assess the metabolic changes with testosterone replacement and indicates a threshold at which symptoms improve with physiological replacement.
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Testosterone Undecanoate improves Sexual Function in Men with Type 2 diabetes and Severe Hypogonadism: Results from a 30 week randomized placebo controlled study.

TL;DR: The sexual function response to 30 weeks’ treatment with long‐acting testosterone undecanoate (TU) or placebo or placebo in 199 men with type 2 diabetes and either severe or mild hypogonadism is evaluated.
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Testosterone replacement therapy: improved sexual desire and erectile function in men with type 2 diabetes following a 30-week randomized placebo-controlled study.

TL;DR: This study confirms TRT leads to changes in SxD and EF at different time points and suggests Sxd and EF changes are related, and suggests sxD change after 6 weeks predicting EF change at 30 weeks is possibly a useful clinical finding.
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Detection and characterisation of bone destruction in murine rheumatoid arthritis using statistical shape models

TL;DR: A fully automated method for obtaining quantitative measurements of bone destruction from volumetric micro‐CT images of a mouse hind paw is presented, suggesting that pathological bone shape changes can be usefully and objectively identified as deviations from the model statistics.
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TNFα depleting therapy improves fertility and animal welfare in TNFα-driven transgenic models of polyarthritis when administered in their routine breeding.

TL;DR: This study is the first to report that regular administration of infliximab is effective at suppressing disease activity and improving animal welfare in TNFΔARE animals and shows that inflixIMab is highly efficacious in improving breeding behaviour and increasing the number of litters sired by TNF ΔARE males.