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Attila Jakab
Researcher at University of Debrecen
Publications - 52
Citations - 1396
Attila Jakab is an academic researcher from University of Debrecen. The author has contributed to research in topics: Sperm & Cancer. The author has an hindex of 14, co-authored 47 publications receiving 1175 citations. Previous affiliations of Attila Jakab include Joseph Fourier University & Yale University.
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Journal ArticleDOI
Intracytoplasmic sperm injection: a novel selection method for sperm with normal frequency of chromosomal aneuploidies
Attila Jakab,Denny Sakkas,Elena Delpiano,Sevil Cayli,Erttig Kovanci,David C. Ward,Alberto Ravelli,Gabor Huszar +7 more
TL;DR: The HA sperm selection method for ICSi, which is based on a relationship between sperm receptors for zona pellucida and HA, will likely reduce the potential genetic complications and adverse public health effects of ICSI.
Journal ArticleDOI
Fertility testing and ICSI sperm selection by hyaluronic acid binding: clinical and genetic aspects.
Gabor Huszar,Attila Jakab,Denny Sakkas,Ciler-Celik Ozenci,Sevil Cayli,Elena Delpiano,Sinan Ozkavukcu +6 more
TL;DR: In HA-selected spermatozoa the frequency of chromosomal disomy and diploidy is reduced 4- to 6-fold compared with semen sperm fractions, similar to the increase in numerical chromosomal aberrations in ICSI children.
Journal ArticleDOI
Biochemical markers of sperm function: male fertility and sperm selection for ICSI.
Sevil Cayli,Sevil Cayli,Attila Jakab,Laszlo Ovari,Elena Delpiano,Ciler Celik-Ozenci,Denny Sakkas,David C. Ward,Gabor Huszar +8 more
TL;DR: The presence of the hyaluronic acid (HA) receptor on the plasma membrane of mature sperm coupled with the HA-coated slide sperm-binding assay, facilitates the testing of infertile men and the selection of single mature spermatozoa for ICSI.
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Sperm selection for ICSI: shape properties do not predict the absence or presence of numerical chromosomal aberrations.
Ciler Celik-Ozenci,Attila Jakab,Tamás Kovács,Jillian S. Catalanotti,Ramazan Demir,Patricia Bray-Ward,David C. Ward,Gabor Huszar +7 more
TL;DR: Sperm dimensions or shape are not reliable attributes in selection of haploid sperm for ICSI because of meiotic errors caused by low levels of the HspA2 chaperone, a component of the synaptonemal complex.
Journal ArticleDOI
Hyaluronic acid binding ability of human sperm reflects cellular maturity and fertilizing potential: selection of sperm for intracytoplasmic sperm injection.
TL;DR: Hyaluronic acid mediated sperm selection is a novel technique that is comparable to sperm zona pellucida binding and will also alleviate the risks related to intracytoplasmic sperm injection fertilization with sperm of diminished maturity that currently cause worldwide concern.