A
Attila Molnar
Researcher at University of Edinburgh
Publications - 67
Citations - 6110
Attila Molnar is an academic researcher from University of Edinburgh. The author has contributed to research in topics: RNA silencing & RNA. The author has an hindex of 28, co-authored 58 publications receiving 5452 citations. Previous affiliations of Attila Molnar include John Innes Centre & Hungarian Academy of Sciences.
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Journal ArticleDOI
Small Silencing RNAs in Plants Are Mobile and Direct Epigenetic Modification in Recipient Cells
Attila Molnar,Charles W. Melnyk,Andrew R. Bassett,Thomas J. Hardcastle,Ruth M. Dunn,David C. Baulcombe +5 more
TL;DR: In Arabidopsis, both exogenous and endogenous small interfering RNAs (siRNAs), rather than their long double-stranded precursor RNAs, are the molecules that transfer information between plant cells and represent a mechanism for transmitting the specification of epigenetic modification.
Journal ArticleDOI
A viral protein suppresses RNA silencing and binds silencing‐generated, 21‐ to 25‐nucleotide double‐stranded RNAs
Dániel Silhavy,Attila Molnar,Alessandra Lucioli,György Szittya,Csaba Hornyik,Mario Tavazza,József Burgyán +6 more
TL;DR: It is proposed that the 19 kDa protein (p19) of tombusviruses is a potent silencing suppressor that prevents the spread of mobile silencing signal by sequestering the PTGS‐generated 21–25 nt dsRNAs, thus depleting the specificity determinants of PTGS effector complexes.
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miRNAs control gene expression in the single-cell alga Chlamydomonas reinhardtii
Attila Molnar,Frank Schwach,Frank Schwach,David J. Studholme,Eva C. Thuenemann,David C. Baulcombe +5 more
TL;DR: The unicellular alga Chlamydomonas reinhardtii is shown to contain miRNAs, putative evolutionary precursors of mi RNAs and species of siRNAs resembling those in higher plants, indicating that complex RNA-silencing systems evolved before multicellularity and were a feature of primitive eukaryotic cells.
Journal ArticleDOI
Low temperature inhibits RNA silencing-mediated defence by the control of siRNA generation
György Szittya,Dániel Silhavy,Attila Molnar,Zoltán Havelda,Agnes Lovas,Lóránt Lakatos,Zsófia Bánfalvi,József Burgyán +7 more
TL;DR: It is shown that in cold, plants become more susceptible to viruses, and RNA silencing‐based phenotypes of transgenic plants are lost, suggesting that the two classes of small RNAs are generated by different nuclease complexes.
Journal ArticleDOI
Plant Virus-Derived Small Interfering RNAs Originate Predominantly from Highly Structured Single-Stranded Viral RNAs
TL;DR: The results suggest that virus-derived siRNAs originate predominantly by direct DICER cleavage of imperfect duplexes in the most folded regions of the positive strand of the viral RNA.