D
David C. Baulcombe
Researcher at University of Cambridge
Publications - 296
Citations - 54020
David C. Baulcombe is an academic researcher from University of Cambridge. The author has contributed to research in topics: RNA & Gene. The author has an hindex of 110, co-authored 287 publications receiving 50828 citations. Previous affiliations of David C. Baulcombe include Norwich Research Park & Sainsbury Laboratory.
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Journal ArticleDOI
A species of small antisense RNA in posttranscriptional gene silencing in plants.
TL;DR: The 25-nucleotide antisense RNA detected in transgene-induced PTGS is likely synthesized from an RNA template and may represent the specificity determinant of PTGS.
Journal ArticleDOI
RNA silencing in plants
TL;DR: Diverse biological roles of these pathways have been established, including defence against viruses, regulation of gene expression and the condensation of chromatin into heterochromatin, and the full extent of this functional diversity in genetic and epigenetic mechanisms of genome control is investigated.
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An enhanced transient expression system in plants based on suppression of gene silencing by the p19 protein of tomato bushy stunt virus.
TL;DR: A system based on co-expression of a viral-encoded suppressor of gene silencing, the p19 protein of tomato bushy stunt virus, that prevents the onset of PTGS in the infiltrated tissues and allows high level of transient expression is described.
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An RNA-Dependent RNA Polymerase Gene in Arabidopsis Is Required for Posttranscriptional Gene Silencing Mediated by a Transgene but Not by a Virus
TL;DR: It is proposed that the role of SDE1 is to synthesize a double-stranded RNA initiator of posttranscriptional gene silencing, according to this idea, when a virus induces posttranscriptal genesilencing, the virus-encoded RNA polymerase would produce the double-Stranded RNA and Sde1 would be redundant.
Journal ArticleDOI
Criteria for Annotation of Plant MicroRNAs
Blake C. Meyers,Michael J. Axtell,Bonnie Bartel,David P. Bartel,David C. Baulcombe,John L. Bowman,Xiaofeng Cao,James C. Carrington,Xuemei Chen,Pamela J. Green,Sam Griffiths-Jones,Steven E. Jacobsen,Allison C. Mallory,Robert A. Martienssen,R. Scott Poethig,Yijun Qi,Hervé Vaucheret,Olivier Voinnet,Yuichiro Watanabe,Detlef Weigel,Jian-Kang Zhu +20 more
TL;DR: The specific criteria required for the annotation of plant miRNAs are updated, including experimental and computational data, as well as refinements to standard nomenclature.