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Austin P. Spicola
Publications - 1
Austin P. Spicola is an academic researcher. The author has contributed to research in topics: Promoter & Gene. The author has co-authored 1 publications.
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Enhancer-Mediated Formation of Nuclear Transcription Initiation Domains
Matthew D. Gibbons,Yuqiang Fang,Austin P. Spicola,Niko Linzer,Stephen M. Jones,Breanna R. Johnson,Lu Li,Mingyi Xie,Jörg Bungert +8 more
TL;DR: It is proposed that there are two modes of Pol II recruitment to enhancers in higher eukaryotes: Pol II complexes that generate eRNAs are recruited via TFIID, similar to mechanisms operating at promoters, and transient contacts with target genes, governed by proteins and RNA, lead to the transfer ofPol II from enhancers to TFIid-bound promoters.