N
Niko Linzer
Researcher at University of Florida
Publications - 3
Citations - 2
Niko Linzer is an academic researcher from University of Florida. The author has contributed to research in topics: Gene & Promoter. The author has co-authored 1 publications.
Papers
More filters
Journal ArticleDOI
Regulation of RNA Polymerase II Transcription Initiation and Elongation by Transcription Factor TFII-I.
Niko Linzer,Alexis Trumbull,Rukiye Nar,Matthew D. Gibbons,David Yu,John Strouboulis,Jörg Bungert +6 more
TL;DR: In this article, the authors reviewed the known functions of TFII-I related to the regulation of RNA polymerase II transcription at the stages of initiation and elongation, and showed that TFII is essential for the development of mice and represents a barrier for the induction of pluripotency.
Journal ArticleDOI
Enhancer-Mediated Formation of Nuclear Transcription Initiation Domains
Matthew D. Gibbons,Yuqiang Fang,Austin P. Spicola,Niko Linzer,Stephen M. Jones,Breanna R. Johnson,Lu Li,Mingyi Xie,Jörg Bungert +8 more
TL;DR: It is proposed that there are two modes of Pol II recruitment to enhancers in higher eukaryotes: Pol II complexes that generate eRNAs are recruited via TFIID, similar to mechanisms operating at promoters, and transient contacts with target genes, governed by proteins and RNA, lead to the transfer ofPol II from enhancers to TFIid-bound promoters.