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Azzam A. Maghazachi
Researcher at University of Sharjah
Publications - 106
Citations - 3956
Azzam A. Maghazachi is an academic researcher from University of Sharjah. The author has contributed to research in topics: Chemokine & Chemokine receptor. The author has an hindex of 31, co-authored 93 publications receiving 3443 citations. Previous affiliations of Azzam A. Maghazachi include Health Sciences North & New York University.
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Journal ArticleDOI
Expression and regulation of chemokine receptors in human natural killer cells
TL;DR: This study examined the expression of chemokine receptors in nonactivated natural killer (NK) cells and compared this expression with NK cells activated with interleukin (IL)-2, which either adhered to plastic flasks (AD) or did not adhere (NA).
Book ChapterDOI
Role of Chemokines in the Biology of Natural Killer Cells
TL;DR: Depending on the tissue and the chemokine secreted, NK cells may ameliorate the disease such as their roles in combating tumors or virally infected cells, and their therapeutic potentials in treating leukemias and other hematological malignancies, as well as reducing the incidence of GvH disease.
Journal ArticleDOI
Suppressive Effect of 1α,25-Dihydroxyvitamin D3 on Type I IFN-Mediated Monocyte Differentiation into Dendritic Cells: Impairment of Functional Activities and Chemotaxis
Maria Cristina Gauzzi,Cristina Purificato,Karim Donato,Yixin Jin,Ling Wang,Kenn C. Daniel,Azzam A. Maghazachi,Filippo Belardelli,Luciano Adorini,Sandra Gessani +9 more
TL;DR: Findings indicate that, in this innovative single-step DC generation model from monocytes, the suppressive effect of 1,25(OH)2D3 is associated with a potent impairment of DC migration in response to inflammatory and lymph node-homing chemokines, thus unraveling a novel mechanism involved in 1, 25(OH), 2D3-mediated immunomodulation.
Journal ArticleDOI
Elevated expression of endothelin-1 and endothelin-converting enzyme-1 in idiopathic pulmonary fibrosis: possible involvement of proinflammatory cytokines.
Dina Saleh,Kanako Furukawa,Ming-Sound Tsao,Azzam A. Maghazachi,Bryan Corrin,Masashi Yanagisawa,Peter J. Barnes,Adel Giaid +7 more
TL;DR: It is demonstrated that the colocalization of the precursor and active ET-1, and ECE-1 in the same cell, and that E CE-1 expression is elevated in IPF, may be mediated by proinflammatory cytokines.
Journal ArticleDOI
CC chemokines induce the generation of killer cells from CD56+ cells.
TL;DR: It is described here that members of the CC chemokines exhibit biological activities other than chemotaxis, and the involvement of T cell‐derived factors in inducing the proliferation of these cells is confirmed.