B. F. Garifullin

TL;DR: The first macrocyclic glycoterpenoids comprising glucosamine and diterpenoid isosteviol moieties were synthesized and evaluated for inhibition activity against Mycobacterium tuberculosis H37Rv.

TL;DR: The parental compounds and their synthetic derivatives were found to inhibit the in vitro growth of Mycobacterium tuberculosis (H37RV) and the maximal inhibitory effect against M. tuberculosis was shown.

TL;DR: The antiviral activity of the 1,2,3-triazolyl nucleoside analogues 4i and 8n against H1N1 (A/PR/8/34) influenza virus can be explained by their influence on the functioning of the polymerase acidic protein (PA) of RNA-dependent RNA polymerase (RdRP).

TL;DR: The minireview survey as mentioned in this paper surveys the modification of native nucleosides as a result of which huge libraries of nucleoside analogs of various structures were synthesized, with particular attention paid to the synthesis of the so-called prodrugs which ensure their penetration into the cell and metabolism to active 5'-triphosphate derivatives.

TL;DR: A series of glycosides and glycoconjugates of diterpenoid isosteviol with various monosaccharide residues were synthesized and their cytotoxicity against some human cancer and normal cell lines was assayed.