B
Bal L. Lokeshwar
Researcher at Charlie Norwood VA Medical Center
Publications - 1
Citations - 117
Bal L. Lokeshwar is an academic researcher from Charlie Norwood VA Medical Center. The author has contributed to research in topics: Cancer & Cell signaling. The author has an hindex of 1, co-authored 1 publications receiving 96 citations.
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Combined inhibition of DNMT and HDAC blocks the tumorigenicity of cancer stem-like cells and attenuates mammary tumor growth
Rajneesh Pathania,Sabarish Ramachandran,G. Mariappan,Priyanka Thakur,Huidong Shi,Jeong Hyeon Choi,Santhakumar Manicassamy,Ravindra Kolhe,Puttur D. Prasad,Suash Sharma,Bal L. Lokeshwar,Vadivel Ganapathy,Muthusamy Thangaraju +12 more
TL;DR: It is suggested that breast CSCs are intrinsically sensitive to genetic and epigenetic modifications and can therefore be significantly affected by epigenetic-based therapies, warranting further investigation of combined DNMT and HDAC inhibition in refractory or drug-resistant breast cancer.