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Balaji Srinivasan

Bio: Balaji Srinivasan is an academic researcher from Indian Institute of Technology Madras. The author has contributed to research in topics: Fiber laser & Fiber Bragg grating. The author has an hindex of 15, co-authored 179 publications receiving 845 citations. Previous affiliations of Balaji Srinivasan include Indian Institutes of Technology & University of New Mexico.


Papers
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Patent
08 Feb 1999
TL;DR: In this paper, the use of a selective voltage input to control the phase, frequency and/or amplitude of a propagating wave in the waveguide is described, and the structure and methods of manufacturing are described.
Abstract: The present invention relates generally to electro-optically active waveguide segments, and more particularly to the use of a selective voltage input to control the phase, frequency and/or amplitude of a propagating wave in the waveguide. Particular device structures and methods of manufacturing are described herein.

78 citations

Journal ArticleDOI
TL;DR: The feasibility of detection of delamination is experimentally demonstrated, whose size is comparable to the ultrasonic wavelength with probability of detection better than 90% using <1% of the total number of samples required for conventional imaging, even under conditions wherein the SNR is as low as 5 dB.

75 citations

Journal ArticleDOI
TL;DR: Experimental results showing the excited OAM mode purity of up to 75% measured through the standard ring technique not only demonstrate the proof of concept but also provide a baseline for further improvement.
Abstract: Orbital angular momentum beam excitation through direct phase-matched coupling is experimentally demonstrated using an all-fiber weakly fused mode selective coupler consisting of a single-mode fiber and a ring-core fiber. Experimental results showing the excited OAM mode purity of up to 75% measured through the standard ring technique not only demonstrate the proof of concept but also provide a baseline for further improvement.

72 citations

Journal ArticleDOI
TL;DR: The demonstration of high power (660 mW) CW operation of a diode-pumped mid-IR Er fiber laser is reported by using efficient depopulation of the lower laser level via enhanced cross-relaxation between Er ions and energy transfer to Pr ions.
Abstract: We report the demonstration of high power (660 mW) CW operation of a diode-pumped mid-IR Er fiber laser. This was achieved by using efficient depopulation of the lower laser level via enhanced cross-relaxation between Er ions and energy transfer to Pr ions (at doping densities much higher than those used previously in Er:ZBLAN), along with optimal pumping of such lasers via custom-designed double-clad fluoride fibers.

72 citations

Posted Content
TL;DR: A generalized deep learning-based framework for histopathology tissue analysis is proposed that has state-of-the-art performance across all these tasks and is ranked within the top 5 currently for the challenges based on these datasets.
Abstract: Histopathology tissue analysis is considered the gold standard in cancer diagnosis and prognosis. Given the large size of these images and the increase in the number of potential cancer cases, an automated solution as an aid to histopathologists is highly desirable. In the recent past, deep learning-based techniques have provided state of the art results in a wide variety of image analysis tasks, including analysis of digitized slides. However, the size of images and variability in histopathology tasks makes it a challenge to develop an integrated framework for histopathology image analysis. We propose a deep learning-based framework for histopathology tissue analysis. We demonstrate the generalizability of our framework, including training and inference, on several open-source datasets, which include CAMELYON (breast cancer metastases), DigestPath (colon cancer), and PAIP (liver cancer) datasets. We discuss multiple types of uncertainties pertaining to data and model, namely aleatoric and epistemic, respectively. Simultaneously, we demonstrate our model generalization across different data distribution by evaluating some samples on TCGA data. On CAMELYON16 test data (n=139) for the task of lesion detection, the FROC score achieved was 0.86 and in the CAMELYON17 test-data (n=500) for the task of pN-staging the Cohen's kappa score achieved was 0.9090 (third in the open leaderboard). On DigestPath test data (n=212) for the task of tumor segmentation, a Dice score of 0.782 was achieved (fourth in the challenge). On PAIP test data (n=40) for the task of viable tumor segmentation, a Jaccard Index of 0.75 (third in the challenge) was achieved, and for viable tumor burden, a score of 0.633 was achieved (second in the challenge). Our entire framework and related documentation are freely available at GitHub and PyPi.

54 citations


Cited by
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Journal ArticleDOI
23 Sep 1974-JAMA
TL;DR: A great strength of the subject of pathology is that it bonds strongly with many other medical sciences and specialties and thus occupies the top spot in the field.
Abstract: Pathologic Basis of Diseaseby Stanley L. Robbins is really the fourth edition of hisPathology. Appropriate updating and addition enhance the otherwise identical format, sequence, writing, and illustrations. So many medical students have benefited from this source that it may be the best known general book in the field. I recommend it even more now. Like his former texts, this will be enjoyed for its readability. He clearly lays out a great deal of information. When he includes minutiae, the reasons are clear and one feels that all the material is pertinent. Robbins keeps the whole field in perspective—that is, he does not dwell so long or so heavily on pathologic anatomy or pathogenesis as to tempt the reader to overlook clinical presentation or prognosis. A great strength of the subject of pathology is that it bonds strongly with many other medical sciences and specialties and thus occupies the

1,230 citations

Journal ArticleDOI
TL;DR: In this paper, the historical progress and the properties of fluoride glass and the fabrication of ZBLAN fibers are briefly described and the constraints on the power scaling of ZblAN fiber lasers are analyzed and discussed.
Abstract: ZBLAN (ZrF4-BaF2-LaF3-AlF3-NaF), considered as the most stable heavy metal fluoride glass and the excellent host for rare-earth ions, has been extensively used for efficient and compact ultraviolet, visible, and infrared fiber lasers due to its low intrinsic loss, wide transparency window, and small phonon energy. In this paper, the historical progress and the properties of fluoride glasses and the fabrication of ZBLAN fibers are briefly described. Advances of infrared, upconversion, and supercontinuum ZBLAN fiber lasers are addressed in detail. Finally, constraints on the power scaling of ZBLAN fiber lasers are analyzed and discussed. ZBLAN fiber lasers are showing promise of generating high-power emissions covering from ultraviolet to mid-infrared considering the recent advances in newly designed optical fibers, beam-shaped high-power pump diodes, beam combining techniques, and heat-dissipating technology.

325 citations