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Barbara A. Hamkalo
Researcher at University of California, Irvine
Publications - 43
Citations - 2080
Barbara A. Hamkalo is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Chromatin & DNA. The author has an hindex of 27, co-authored 43 publications receiving 2038 citations. Previous affiliations of Barbara A. Hamkalo include University of California, Berkeley & Colorado State University.
Papers
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Journal ArticleDOI
Curvature of mouse satellite DNA and condensation of heterochromatin.
TL;DR: It is hypothesize that the structure of mouse satellite DNA is an important feature of centromeric heterochromatin condensation, and that satellite does not comprise a single block but is distributed throughout the centromere region.
Patent
Isolation of biological materials using magnetic particles
TL;DR: In this paper, a method for the isolation and sorting of biological materials has been developed, which is an alternative to flow cytometry and presents numerous advantages in terms of time, resolution, purity, and preservation of the structure of the biological material during isolation and separation.
Journal ArticleDOI
Characterization of a cloned repetitive DNA sequence concentrated on the human X chromosome
TL;DR: A tandemly repeated DNA sequence organized predominantly, if not entirely, in a specific manner on the human X chromosome has been cloned in pBR322 and characterized and it is suggested that the 2-kilobase spacing of BamHI sites within the repeat may be specific to the X chromosome.
Journal ArticleDOI
In situ hybridization at the electron microscope level: hybrid detection by autoradiography and colloidal gold
TL;DR: Two methods to extend this technique to the transmission electron microscope level using mouse satellite DNA hybridization to whole mount metaphase chromosomes as the test system are developed and possesses the potential to allow precise ultrastructual localization of DNA sequences in chromosomes and chromatin.
Journal ArticleDOI
A compendium of the histone H1 family of somatic subtypes: An elusive cast of characters and their characteristics
TL;DR: The goal of the following review is to acquaint the reader with the ubiquitous somatic H1 subtypes by categorizing them and their characteristics into several classes by proposing a model that may explain the functional role of H1 heterogeneity in chromatin compaction.