Bárbara B. Garrido-Suárez

TL;DR: Vimang is an aqueous extract of Mangifera indica L. traditionally used in Cuba for its analgesic, anti-inflammatory, antioxidant and immunomodulatory properties, and also for mangiferin, its major component, which has potential utility in the neuropathic pain treatment.

TL;DR: It is suggested that MG shows ability to decrease tonic pain in the formalin test and its neuroprotective effect by preventing WD in mononeuropathic rats could be implicated in the mechano-antihypernociceptive long term mechanisms.

TL;DR: Data constitute the first report that suggested the participation, at least in part, of the L-arginine-NOS-NO-GMPc pathway activation in anti-hyperalgesic effect of EA in carrageenan-induced inflammation model.

TL;DR: Treatment's efficacy was demonstrated with ACR criteria and only the patients of MTX‐Vimang group revealed statistically significant improvement in DAS 28 parameters with respect baseline data but no differences were observed between groups.

TL;DR: Mangiferin (MG) is a glucosylxanthone that is broadly distributed in higher plants, and its potential utility as a multitargeted compound for mixed OA pain, even in the context of multimodal pharmacotherapy is proposed.