Barbara Handelin

TL;DR: Together the hMR and hGR provide unexpected functional diversity in which hormone-binding properties, target gene interactions, and patterns of tissue-specific expression may be used in a combinatorial fashion to achieve complex physiologic control.

TL;DR: An improved system for the production of a series of rodent-human hybrids selectively retaining single human chromosomes marked in known locations is described, which has significant applications in gene mapping and other genetic studies.

TL;DR: A modification of the method first developed by Goss and Harris for generation of irradiation hybrids used to obtain new polymorphic markers for Huntington's disease and identified 41 single-copy fragments, of which 27 have been mapped to specific regions of chromosome 4.

TL;DR: The data presented here suggest that in several hybrid derivatives of J1, a continuous DNA segment of approximately 107base pairs in length which includes the insulin and HRAS1 genes has been isolated from the remainder of the human genome.

TL;DR: In this article , the authors describe the considerations of payers and how these translate to signals for research and development by producers, and elaborate a business model that exchanges some of the profit motives with the prioritisation of medical value.