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Barbara Kell
Researcher at St Thomas' Hospital
Publications - 15
Citations - 471
Barbara Kell is an academic researcher from St Thomas' Hospital. The author has contributed to research in topics: Papillomaviridae & Cervical intraepithelial neoplasia. The author has an hindex of 10, co-authored 15 publications receiving 464 citations. Previous affiliations of Barbara Kell include King University.
Papers
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Journal ArticleDOI
Perinatal infection and persistence of human papillomavirus types 16 and 18 in infants
John Cason,Jeremy N. Kaye,Richard J. Jewers,Parminder K. Kambo,Jon M. Bible,Barbara Kell,Bhavneet Shergill,Farzin Pakarian,K. Shanti Raju,Jennifer M. Best +9 more
TL;DR: Investigation of whether HPV‐16 and ‐18 DNA in infants contaminated at delivery persists until they are 6 months of age found bimodal distribution of IgM seropositivity peaked between 2 and 5 and 13 and 16 years of age, suggesting that two distinct modes of transmission may occur.
Journal ArticleDOI
Viral load as a determinant for transmission of human papillomavirus type 16 from mother to child.
Jeremy N. Kaye,John Cason,Farzin Pakarian,Richard J. Jewers,Barbara Kell,Jon M. Bible,Kankipati S. Raju,Jennifer M. Best +7 more
TL;DR: It is concluded that viral load is an important, but not the sole, determinant for the transmission of HPV‐16 from mother to infant.
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Detection of E5 oncoprotein in human papillomavirus type 16-positive cervical scrapes using antibodies raised to synthetic peptides.
TL;DR: The apparent M(r) by SDS-PAGE suggests that HPV-16 E5 forms homodimers in vivo, but not through cysteine linkage, and is likely to be related to cervical intraepithelial neoplasia.
Journal ArticleDOI
Human papillomavirus type 16 in infants: use of DNA sequence analyses to determine the source of infection.
Jeremy N. Kaye,William G. Starkey,Barbara Kell,Chandrima Biswas,Kankipati S. Raju,J. M. Best,John Cason +6 more
TL;DR: Conordant variants or prototypic sequences were detected in nine of 13 mother/infant samples, indicating that up to 69.2% of HPV-16-positive infants acquire virus from their mothers.
Journal ArticleDOI
Analytic sensitivities of hybrid-capture, consensus and type-specific polymerase chain reactions for the detection of human papillomavirus type 16 DNA.
Saban Cavuslu,Christine Mant,William G. Starkey,Jon M. Bible,Chandrima Biswas,Barbara Kell,Philip Rice,Jennifer M. Best,John Cason +8 more
TL;DR: The analytical sensitivities of Hybrid Capture, HPV‐consensus PCR, and three HPV‐16‐specific polymerase chain reactions (PCRs) for the detection of HPV‐ 16 DNA are determined and indicate that HPV‐15 type‐specific PCRs should be used for the investigation of specimens that may contain low amounts of HPV16 DNA.