J
John Cason
Researcher at King's College London
Publications - 91
Citations - 3145
John Cason is an academic researcher from King's College London. The author has contributed to research in topics: Cervical intraepithelial neoplasia & Biobank. The author has an hindex of 28, co-authored 90 publications receiving 2684 citations. Previous affiliations of John Cason include Guy's and St Thomas' NHS Foundation Trust & Applied Science Private University.
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Journal ArticleDOI
A dynamic COVID-19 immune signature includes associations with poor prognosis.
Adam Laing,Anna Lorenc,Irene del Molino del Barrio,Irene del Molino del Barrio,Abhishek Das,Abhishek Das,Matthew Fish,Matthew Fish,Leticia Monin,Miguel Muñoz-Ruiz,Duncan R. McKenzie,Thomas Hayday,Isaac Francos-Quijorna,Shraddha Kamdar,Magdalene Joseph,Daniel Davies,Daniel Davies,Richard Davis,Aislinn Jennings,Aislinn Jennings,Iva Zlatareva,Pierre Vantourout,Yin Wu,Yin Wu,Yin Wu,Vasiliki Sofra,Florencia Cano,Maria Greco,Efstathios Theodoridis,Joshua D. Freedman,Sarah Gee,Julie Nuo En Chan,Sarah Ryan,Eva Bugallo-Blanco,Pärt Peterson,Kai Kisand,Liis Haljasmägi,Loubna Chadli,Philippe Moingeon,Lauren Martinez,Blair Merrick,Karen Bisnauthsing,Kate Brooks,Mohammad A. A. Ibrahim,Jeremy Mason,Federico Lopez Gomez,Kola Babalola,Sultan Abdul-Jawad,John Cason,Christine Mant,Jeffrey Seow,Carl Graham,Katie J. Doores,Francesca Di Rosa,Jonathan D. Edgeworth,Manu Shankar-Hari,Manu Shankar-Hari,Adrian Hayday,Adrian Hayday +58 more
TL;DR: A core peripheral blood immune signature is identified across 63 hospital-treated patients with COVID-19 who were otherwise highly heterogeneous and sheds light into the pathogenesis and clinical progression of the disease.
Journal ArticleDOI
Perinatal infection and persistence of human papillomavirus types 16 and 18 in infants
John Cason,Jeremy N. Kaye,Richard J. Jewers,Parminder K. Kambo,Jon M. Bible,Barbara Kell,Bhavneet Shergill,Farzin Pakarian,K. Shanti Raju,Jennifer M. Best +9 more
TL;DR: Investigation of whether HPV‐16 and ‐18 DNA in infants contaminated at delivery persists until they are 6 months of age found bimodal distribution of IgM seropositivity peaked between 2 and 5 and 13 and 16 years of age, suggesting that two distinct modes of transmission may occur.
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Adjuvanted influenza-H1N1 vaccination reveals lymphoid signatures of age-dependent early responses and of clinical adverse events
Olga Sobolev,Olga Sobolev,Elisa Binda,Elisa Binda,Sean O'Farrell,Sean O'Farrell,Anna Lorenc,Joel Pradines,Yongqing Huang,Jay Duffner,Reiner Schulz,John Cason,Maria Zambon,Michael H. Malim,Mark Peakman,Andrew P. Cope,Ishan Capila,Ganesh Kaundinya,Adrian Hayday,Adrian Hayday +19 more
TL;DR: Within 24 h of receiving adjuvanted swine flu vaccine, healthy individuals made expansive, complex molecular and cellular responses that included overt lymphoid as well as myeloid contributions, and this early response was subtly but significantly different in people older than ∼35 years.
Journal Article
Interleukin 1 in Crohn's disease.
TL;DR: Enhanced production of LAF in vitro may reflect a primary cellular defect in Crohn's disease, or a secondary consequence of monocyte activation, according to the mouse thymocyte stimulation assay.
Journal ArticleDOI
High risk of human papillomavirus type 16 infections and of development of cervical squamous intraepithelial lesions in systemic lupus erythematosus patients
Rahul Nath,Christine Mant,Jennifer Luxton,Graham R. V. Hughes,K. Shanti Raju,Phillip Shepherd,John Cason,John Cason +7 more
TL;DR: UK women with a recent SLE diagnosis had disturbingly elevated levels of HPV infections (particularly with European HPV-16 variants at a high viral load), abnormal cervical cytology, and SIL.