B
Barbara Winsor
Researcher at Centre national de la recherche scientifique
Publications - 26
Citations - 2997
Barbara Winsor is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Actin cytoskeleton & Arp2/3 complex. The author has an hindex of 20, co-authored 26 publications receiving 2864 citations. Previous affiliations of Barbara Winsor include University of Strasbourg.
Papers
More filters
Journal ArticleDOI
Epitope tagging of yeast genes using a PCR‐based strategy: more tags and improved practical routines
Michael Knop,Katja Siegers,Gislene Pereira,Wolfgang Zachariae,Barbara Winsor,Kim Nasmyth,Elmar Schiebel +6 more
TL;DR: In the yeast Saccharomyces cerevisiae, molecular biological techniques have been developed that use a simple PCR‐based strategy to introduce epitope tags to chromosomal loci to produce PCR amplificable modules.
Journal ArticleDOI
Direct regulation of Arp2/3 complex activity and function by the actin binding protein coronin
Christine Humphries,Heath I. Balcer,Jessica L. D'Agostino,Barbara Winsor,David G. Drubin,Georjana Barnes,Brenda J. Andrews,Bruce L. Goode +7 more
TL;DR: In vivo evidence that coronin regulates the Arp2/3 complex comes from the observation that crn1 and arp2 mutants display an allele-specific synthetic interaction, and this work identifies a new form of regulation of the ArP2/ 3 complex and an important cellular function for coronin.
Journal ArticleDOI
The BAR Domain Proteins: Molding Membranes in Fission, Fusion, and Phagy
TL;DR: The cellular roles of BAR domain proteins, characterized over the past decade in cells as distinct as yeasts, neurons, and myocytes, can be understood in terms of a fundamental molecular function: to sense membrane curvature, to bind GTPases, and to mold a diversity of cellular membranes.
Journal ArticleDOI
Bayesian Modeling of the Yeast SH3 Domain Interactome Predicts Spatiotemporal Dynamics of Endocytosis Proteins
Raffi Tonikian,Xiaofeng Xin,Christopher P. Toret,David Gfeller,Christiane Landgraf,Simona Panni,Simona Panni,Serena Paoluzi,Luisa Castagnoli,Bridget Currell,Somasekar Seshagiri,Haiyuan Yu,Barbara Winsor,Marc Vidal,Mark Gerstein,Gary D. Bader,Rudolf Volkmer,Gianni Cesareni,David G. Drubin,Philip M. Kim,Sachdev S. Sidhu,Charles Boone +21 more
TL;DR: A genome-scale specificity and interaction map for yeast SH3 domain-containing proteins reveal how family members show selective binding to target proteins and predicts the dynamic localization of new candidate endocytosis proteins.
Journal ArticleDOI
The Saccharomyces cerevisiae Homologue of Human Wiskott–Aldrich Syndrome Protein Las17p Interacts with the Arp2/3 Complex
Ammar Madania,Pascal Dumoulin,Sandrine Grava,Hiroko Kitamoto,Claudia Schärer-Brodbeck,Alexandre Soulard,Violaine Moreau,Barbara Winsor +7 more
TL;DR: Two hybrid results suggest that Las17p interacts with actin, verprolin, Rvs167p and several other proteins including Src homology 3 (SH3) domain proteins, suggesting thatLas17p may integrate signals from different regulatory cascades destined for the Arp2/3p complex and the actin cytoskeleton.