B
Bärbel Hahn-Hägerdal
Researcher at Lund University
Publications - 272
Citations - 27781
Bärbel Hahn-Hägerdal is an academic researcher from Lund University. The author has contributed to research in topics: Xylose & Fermentation. The author has an hindex of 83, co-authored 271 publications receiving 26753 citations. Previous affiliations of Bärbel Hahn-Hägerdal include Stellenbosch University & Technical University of Denmark.
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Journal ArticleDOI
Xylose reductase from Pichia stipitis with altered coenzyme preference improves ethanolic xylose fermentation by recombinant Saccharomyces cerevisiae
TL;DR: When the K270R XR was combined with a metabolic engineering strategy that ensures high xylose utilization capabilities, a recombinant S. cerevisiae strain was created that provides a unique combination of highxylose consumption rate, high ethanol yield and low xylitol yield during ethanolic xylOSE fermentation.
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Simultaneous detoxification and enzyme production of hemicellulose hydrolysates obtained after steam pretreatment
TL;DR: In the process of making ethanol from lignocellulosic materials, compounds inhibitory to microorganisms are generated during steam pretreatment of the wood as discussed by the authors, and pentoses are liberated and washed from the cellulose structure which is further enzymatically hydrolyzed.
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Deletion of the GRE3 aldose reductase gene and its influence on xylose metabolism in recombinant strains of Saccharomyces cerevisiae expressing the xylA and XKS1 genes.
TL;DR: An unspecific aldose reductase (AR) capable of reducing xylose to xylitol has been identified in Saccharomyces cerevisiae and was identified in recombinant strains from which the GRE3 gene was deleted.
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SO2-catalyzed steam pretreatment and fermentation of enzymatically hydrolyzed sugarcane bagasse
Cristhian Carrasco,Cristhian Carrasco,Henrique Macedo Baudel,Henrique Macedo Baudel,Johan Sendelius,Tobias Modig,Christian Roslander,Mats Galbe,Bärbel Hahn-Hägerdal,Guido Zacchi,Gunnar Lidén +10 more
TL;DR: In this article, bagasse was steam pretreated at temperatures between 180 and 205 ◦C, with holding times of 5-10 min using SO2 as a catalyst to determine conditions that provide a good recovery of pentoses and a suitable material for enzymatic hydrolysis.
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Generation of the improved recombinant xylose-utilizing Saccharomyces cerevisiae TMB 3400 by random mutagenesis and physiological comparison with Pichia stipitis CBS 6054
C. Fredrik Wahlbom,Willem H. van Zyl,Leif J. Jönsson,Bärbel Hahn-Hägerdal,Ricardo R. Cordero Otero +4 more
TL;DR: It is demonstrated that a combination of metabolic engineering and random mutagenesis was successful to generate a superior, xylose-utilizing S. cerevisiae, and uncovered distinctive physiological properties of the mutant.